Academic Journal
Validation of a User-Friendly and Rapid Method for Quantifying Iodine Content of Salt
| العنوان: | Validation of a User-Friendly and Rapid Method for Quantifying Iodine Content of Salt |
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| المؤلفون: | Rohner, Fabian, Garrett, Greg S., Laillou, Arnaud, Frey, Simone K., Mothes, Ralf, Schweigert, Florian J., Locatelli-Rossi, Lorenzo |
| المصدر: | Food and Nutrition Bulletin ; volume 33, issue 4_suppl3, page S330-S335 ; ISSN 0379-5721 1564-8265 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2012 |
| الوصف: | Background Despite considerable progress made in the past decade through salt iodization programs, over 2 billion people worldwide still have inadequate iodine intake, with devastating consequences for brain development and intellectual capacity. To optimize these programs with regard to salt iodine content, careful monitoring of salt iodine content is essential, but few methods are available to quantitatively measure iodine concentration in a simple, fast, and safe way. Objective We have validated a newly developed device that quantitatively measures the content of potassium iodate in salt in a simple, safe, and rapid way. Methods The linearity, determination and detection limit, and inter- and intra-assay variability of this colorimetric method were assessed and the method was compared with iodometric titration, using salt samples from several countries. Results Linearity of analysis ranged from 5 to 75 mg/kg iodine, with 1 mg/kg being the determination limit; the intra- and interassay imprecision was 0.9%, 0.5%, and 0.7% and 1.5%, 1.7%, and 2.5% for salt samples with iodine contents of 17, 30, and 55 mg/kg, respectively; the interoperator imprecision for the same samples was 1.2%, 4.9%, and 4.7%, respectively. Comparison with the iodometric method showed high agreement between the methods ( R 2 = 0.978; limits of agreement, −10.5 to 10.0 mg/kg). Conclusions The device offers a field- and user-friendly solution to quantifying potassium iodate salt content reliably. For countries that use potassium iodide in salt iodization programs, further validation is required. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1177/15648265120334s309 |
| DOI: | 10.1177/15648265120334S309 |
| الاتاحة: | https://doi.org/10.1177/15648265120334s309 https://journals.sagepub.com/doi/pdf/10.1177/15648265120334S309 |
| Rights: | https://journals.sagepub.com/page/policies/text-and-data-mining-license |
| رقم الانضمام: | edsbas.A3FEEC96 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/15648265120334s309 |
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