Academic Journal

Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region—Results from the Safe Implementation of Treatments in Stroke (SITS)–Middle-East and North African (MENA)

التفاصيل البيبلوغرافية
العنوان: Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region—Results from the Safe Implementation of Treatments in Stroke (SITS)–Middle-East and North African (MENA)
المؤلفون: Rukn, Suhail Al, Mazya, Michael V, Hentati, Faycal, Sassi, Samia Ben, Nabli, Fatma, Said, Zakharia, Faouzi, Belahsen, Hashim, Husnain, Abd-Allah, Foad, Mansouri, Benhan, Kesraoui, Selma, Gebeily, Souheil, Abdulrahman, Husen, Akhtar, Naveed, Ahmed, Niaz, Wahlgren, Nils, Aref, Hany, Almekhlafi, Mohammed, Moreira, Tiago
المساهمون: Boehringer Ingelheim
المصدر: International Journal of Stroke ; volume 14, issue 7, page 715-722 ; ISSN 1747-4930 1747-4949
بيانات النشر: SAGE Publications
سنة النشر: 2019
الوصف: Background and methods Stroke incidence and mortality are reported to have increased in the Middle-East and North African (MENA) countries during the last decade. This was a prospective observational study to examine the baseline characteristics of stroke patients in the MENA region and to compare the MENA vs. the non-MENA stroke cohort in the Safe Implementation of Treatments in Stroke (SITS) International Registry. Results Of the 13,822 patients with ischemic and hemorrhagic stroke enrolled in the SITS-All Patients Protocol between June 2014 and May 2016, 5897 patients (43%) were recruited in MENA. The median onset-to-door time was 5 h (IQR: 2:20–13:00), National Institutes of Health Stroke Scale (NIHSS) score was 8 (4–13) and age was 65 years (56–76). Hypertension (66%) and diabetes (38%) were the prevailing risk factors; large artery stenosis > 50% (25.3%) and lacunar strokes (24.1%) were the most common ischemic stroke etiologies. In comparison, non-MENA countries displayed an onset-to-door time of 5:50 h (2:00–18:45), a median of NIHSS 6 (3–14), and a median age of 66 (56–76), with other large vessel disease and cardiac embolism as the main ischemic stroke etiologies. Hemorrhagic strokes (10%) were less common compared to non-MENA countries (13.9%). In MENA, only a low proportion of patients (21%) was admitted to stroke units. Conclusions MENA patients are slightly younger, have a higher prevalence of diabetes and slightly more severe ischemic strokes, commonly of atherosclerotic or microvascular etiology. Admission into stroke units and long-term follow-up need to be improved. It is suspected that cardiac embolism and atrial fibrillation are currently underdiagnosed in MENA countries.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/1747493019830331
الاتاحة: https://doi.org/10.1177/1747493019830331
https://journals.sagepub.com/doi/pdf/10.1177/1747493019830331
https://journals.sagepub.com/doi/full-xml/10.1177/1747493019830331
Rights: https://journals.sagepub.com/page/policies/text-and-data-mining-license
رقم الانضمام: edsbas.A2F7499F
قاعدة البيانات: BASE
الوصف
DOI:10.1177/1747493019830331