Academic Journal
Long-term psychological distress in breast cancer survivors and their matched controls:A cross-sectional study
| العنوان: | Long-term psychological distress in breast cancer survivors and their matched controls:A cross-sectional study |
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| المؤلفون: | Accord-Maass, Saskia, Boerman, Liselotte, Verhaak, Peter, Du, J, de Bock, Gertruida H, Berendsen, Annette |
| المصدر: | Accord-Maass , S , Boerman , L , Verhaak , P , Du , J , de Bock , G H & Berendsen , A 2019 , ' Long-term psychological distress in breast cancer survivors and their matched controls : A cross-sectional study ' , Maturitas , vol. 130 , pp. 6-12 . https://doi.org/10.1016/j.maturitas.2019.09.003 |
| سنة النشر: | 2019 |
| المجموعة: | University of Groningen research database |
| مصطلحات موضوعية: | Breast neoplasms, Cross-sectional studies, Long-term adverse effects, Survivors, Primary health care, Depression, Anxiety, QUALITY-OF-LIFE, DEPRESSION SCALE HADS, HOSPITAL ANXIETY, PRIMARY-CARE, PREVALENCE, ASSOCIATION, SYMPTOMS, FATIGUE, GENDER, WOMEN |
| الوصف: | Introduction: Breast cancer survivors often experience psychological distress shortly after diagnosis. Long-term psychological effects, however, have not been clearly demonstrated. Methods: This cross-sectional cohort study included 350 breast cancer survivors and 350 age-matched and general-practitioner-matched women. The median follow-up was 10 years. Using logistic regression we compared breast cancer survivors with controls on having (severe) symptoms of depression and/or anxiety, as measured with the Hospital Anxiety and Depression Scale. In multivariable logistic regression, we adjusted the results for a history of depression or prescription of antidepressants. Results: Larger proportions of breast cancer survivors experienced symptoms of depression (10.6%) compared with controls (4.9%) and symptoms of anxiety (18.6%) compared with controls (16.3%). The odds of symptoms of depression (OR 2.3, 95%CI 1.3-4.2), severe symptoms of depression (OR 3.3, 95%CI 1.1-10.3) and severe symptoms of anxiety (OR 2.1, 95%CI, 1.1-4.0) were significantly higher for breast cancer survivors than for controls, even after adjusting for history of depression or prescription of antidepressants. No significant difference was seen for mild symptoms of anxiety. Conclusions: Breast cancer survivors have an increased risk of symptoms of depression, including severe symptoms, and severe symptoms of anxiety compared with controls, for up to at least 10 years after diagnosis. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1016/j.maturitas.2019.09.003 |
| الاتاحة: | https://hdl.handle.net/11370/25d8c303-d3e6-4f33-ad15-2e28ce588ae0 https://research.rug.nl/en/publications/25d8c303-d3e6-4f33-ad15-2e28ce588ae0 https://doi.org/10.1016/j.maturitas.2019.09.003 https://pure.rug.nl/ws/files/97429066/Maass_et_al_Maturitas.pdf |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.A28A19E2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.maturitas.2019.09.003 |
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