Academic Journal

Risk Factors and Outcomes of Children with Congenital Heart Disease on Extracorporeal Membrane Oxygenation—A Ten-Year Single-Center Report

التفاصيل البيبلوغرافية
العنوان: Risk Factors and Outcomes of Children with Congenital Heart Disease on Extracorporeal Membrane Oxygenation—A Ten-Year Single-Center Report
المؤلفون: Antonio Amodeo, Milena Stojanovic, Tugba Erdil, Hitendu Dave, Robert Cesnjevar, Sebastian Paal, Oliver Kretschmar, Martin Schweiger
المصدر: Life; Volume 13; Issue 7; Pages: 1582
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2023
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: complications, congenital heart disease, ECMO, extracorporeal life support, mortality, risk factors, single ventricle
جغرافية الموضوع: agris
الوصف: For children born with congenital heart defects (CHDs), extracorporeal life support may be necessary. This retrospective single-center study aimed to investigate the outcomes of children with CHDs on extracorporeal membrane oxygenation (ECMO), focusing on various risk factors. Among the 88 patients, 36 (41%) had a single-ventricle heart defect, while 52 (59%) had a biventricular defect. In total, 25 (28%) survived, with 7 (8%) in the first group and 18 (20%) in the latter. A p-value of 0.19 indicated no significant difference in survival rates. Children with biventricular hearts had shorter ECMO durations but longer stays in the intensive care unit. The overall rate of complications on ECMO was higher in children with a single ventricle (odds ratio [OR] 1.57, 95% confidence interval [CI] 0.67–3.7); bleeding was the most common complication in both groups. The occurrence of a second ECMO run was more frequent in patients with a single ventricle (22% vs. 9.6%). ECMO can be effective for children with congenital heart defects, including single-ventricle patients. Bleeding remains a serious complication associated with worse outcomes. Patients requiring a second ECMO run within 30 days have lower survival rates.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Physiology and Pathology; https://dx.doi.org/10.3390/life13071582
DOI: 10.3390/life13071582
الاتاحة: https://doi.org/10.3390/life13071582
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.A237D9EE
قاعدة البيانات: BASE