Academic Journal
Medical treatment of early stage and rare histological variants of epithelial ovarian cancer
| العنوان: | Medical treatment of early stage and rare histological variants of epithelial ovarian cancer |
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| المؤلفون: | Cont, Nicoletta Tomasi, Peccatori, Fedro Alessandro, Codacci Pisanelli, Giovanni, Colombo, Nicoletta, Ferrero, Annamaria, D'ALONZO, Marta, BIGLIA, Nicoletta |
| المساهمون: | Cont, Nicoletta Tomasi, Ferrero, Annamaria, Peccatori, Fedro Alessandro, D'Alonzo, Marta, Codacci-Pisanelli, Giovanni, Colombo, Nicoletta, Biglia, Nicoletta |
| سنة النشر: | 2015 |
| المجموعة: | Università degli studi di Torino: AperTo (Archivio Istituzionale ad Accesso Aperto) |
| مصطلحات موضوعية: | biological marker, ovarian neoplasm, personalised medicine |
| الوصف: | Epithelial ovarian cancer is often considered a single pathological entity, but increasing evidence suggests that it is rather a group of different neoplasms, each with unique pathological characteristics, molecular features, and clinical behaviours. This heterogeneity accounts for the different sensitivity to antineoplastic drugs and makes the treatment of ovarian tumours a challenge. For early-stage disease, as well as for heavily pre-treated patients with recurrent ovarian cancer, the benefit of chemotherapy remains uncertain. Clear-cell, mucinous, low-grade serous, and endometrioid carcinomas show different molecular characteristics, which require different therapeutic approaches. In the era of personalised cancer medicine, understanding the pathogenesis and the genetic background of each subtype of epithelial ovarian tumour may lead to a tailored therapy, maximising the benefits of specific treatments and possibly reducing the side effects. Furthermore, personal factors, such as the patient's performance status, should be taken into account in the management of ovarian cancer, with the aim of safeguarding the patients' quality of life. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/26557882; info:eu-repo/semantics/altIdentifier/wos/WOS:000364004400001; volume:9; firstpage:1; lastpage:11; numberofpages:11; journal:ECANCERMEDICALSCIENCE; http://hdl.handle.net/2318/1530192; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84960350844; http://www-ncbi-nlm-nih-gov.offcampus.dam.unito.it/pmc/articles/pmid/26557882/ |
| DOI: | 10.3332/ecancer.2015.584 |
| الاتاحة: | http://hdl.handle.net/2318/1530192 https://doi.org/10.3332/ecancer.2015.584 http://www-ncbi-nlm-nih-gov.offcampus.dam.unito.it/pmc/articles/pmid/26557882/ |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.A1C527A3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3332/ecancer.2015.584 |
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