Academic Journal
The Follicle-Stimulating Hormone as Best Classifier for Diagnosis of Natural Menopause
| العنوان: | The Follicle-Stimulating Hormone as Best Classifier for Diagnosis of Natural Menopause |
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| المؤلفون: | Polesel, Daniel Ninello UNIFESP, Nozoe, Karen T. UNIFESP, Sanchez, Zila M. UNIFESP, Prado, Mariangela C. O. UNIFESP, Bittencourt, Lia R. UNIFESP, Tufik, Sergio UNIFESP, Andersen, Monica L. UNIFESP, Hachul, Helena UNIFESP |
| بيانات النشر: | Mary Ann Liebert, Inc |
| سنة النشر: | 2017 |
| المجموعة: | Universidade Federal de São Paulo (UNIFESP): Repositório Institucional |
| مصطلحات موضوعية: | menopause, sleep, follicle-stimulating hormone, aging, health, women |
| جغرافية الموضوع: | New Rochelle |
| الوصف: | Objective: The aim of this study was to examine the cut-off value of parameters related to menopause in women recruited through the Sao Paulo Epidemiologic Sleep Study. Materials and Methods: A household survey sample of 397 women was submitted to biochemical analysis after overnight fasting for determination of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol levels. Volunteers were randomly selected to represent the population of SAo Paulo according to gender, age, and socioeconomic status. The cut-off values were determined from the receiver operating characteristic curve and by determining the accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of the parameters. Results: FSH, LH, and age provided >90% accuracy for defining the menopause group. Classification of menopause according to FSH level provided the highest level of accuracy (97.0%) based on a cut-off value of 21 mIU/mL as a classifier. Conclusions: The cut-off value for FSH alone was able to distinguish with higher efficiency premenopause and postmenopause groups. FSH levels provided greater accuracy in the diagnosis of natural menopause, compared to the other parameters. ; Associacao Fundo de Incentivo a Pesquisa (AFIP) ; Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) ; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) ; Sao Paulo Research Foundation (FAPESP) ; CNPq ; Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, SP, Brazil ; Univ Fed Sao Paulo, Dept Prevent Med, Sao Paulo, SP, Brazil ; Univ Fed Sao Paulo, Dept Gynecol, Sao Paulo, SP, Brazil ; Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, SP, Brazil ; Univ Fed Sao Paulo, Dept Prevent Med, Sao Paulo, SP, Brazil ; Univ Fed Sao Paulo, Dept Gynecol, Sao Paulo, SP, Brazil ; FAPESP: 2013/14945-7 ; Web of Science |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 236-242 |
| اللغة: | English |
| تدمد: | 1042-4067 |
| Relation: | Journal Of Gynecologic Surgery; http://dx.doi.org/10.1089/gyn.2017.0040; Journal Of Gynecologic Surgery. New Rochelle, v. 33, n. 6, p. 236-242, 2017.; https://repositorio.unifesp.br/handle/11600/58095; WOS:000417632900004 |
| DOI: | 10.1089/gyn.2017.0040 |
| الاتاحة: | https://repositorio.unifesp.br/handle/11600/58095 https://doi.org/10.1089/gyn.2017.0040 |
| Rights: | Acesso restrito |
| رقم الانضمام: | edsbas.A14C24E4 |
| قاعدة البيانات: | BASE |
| تدمد: | 10424067 |
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| DOI: | 10.1089/gyn.2017.0040 |