Academic Journal
Costs and control strategies of healthcare-associated infections in an Italian university hospital
| العنوان: | Costs and control strategies of healthcare-associated infections in an Italian university hospital |
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| المؤلفون: | Mosconi, C, De Santo, C, Ciccacci, F, Carestia, M, Guarente, L, Di Giovanni, D, Morlino, G, Moramarco, S, Cicala, M, Orlando, S |
| المصدر: | European Journal of Public Health ; volume 33, issue Supplement_2 ; ISSN 1101-1262 1464-360X |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2023 |
| الوصف: | Backgrounds Healthcare-associated infections (HAIs) increase morbidity, mortality, and costs, necessitating effective prevention strategies. This study estimates the additional costs of HAIs in a university hospital in Rome, Italy Policlinico Tor Vergata (PTV), to inform policymakers, healthcare professionals, and researchers. Methods We conducted a retrospective cohort study, including all patients admitted or discharged in 2018. We applied propensity score matching (PSM) to balance study groups and then we analysed cost differences using the average treatment effect on the treated (ATT) approach. Costs were calculated using the Diagnosis Related Groups (DRGs) system. Outcome measures included the real reimbursement cost in euros and the relative cost increment using adjusted logarithmic transformation. Results 12,033 patients were included: 6,653(55%) female, 5,380 (45%) male, with a median age of 67. In total, 1,212 (10.1%) infected patients were compared to 10,821 (89.9%) non-infected patients. Predominant infections were urinary tract infections (UTI) (48.8%) and blood stream infections (BSI) (34.4%), while Staphylococcus spp. (37.5%) and Enterococcus spp. (36.4%) were the most common pathogens. The propensity score analysis showed a 59.7% (95% CI: 48.8% to 71.3%) cost increase for infected patients. They incurred an additional €4,988 (95% CI: €4,173 to €5,804) in costs. Subgroup analyses revealed cost variations across infection sites and pathogens, with Klebsiella P. having the greatest economic impact at €7,586 (95% CI: €5,301 to €9,871) and BSI also at €9,719 (95% CI: €8,137 to €11,307). Conclusions This study highlights the significant additional cost burden of HAIs in the PTV. Interventions with an equal or lower cost per HAI averted can be considered cost-effective. Public health actions, including enhancing infection prevention, developing or revising policies, and strengthening surveillance systems, should be prioritised to address ongoing HAI challenges. Key messages • Our study reveals a ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/eurpub/ckad160.747 |
| الاتاحة: | https://doi.org/10.1093/eurpub/ckad160.747 https://academic.oup.com/eurpub/article-pdf/33/Supplement_2/ckad160.747/52418424/ckad160.747.pdf |
| Rights: | https://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.A01D5C2D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/eurpub/ckad160.747 |
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