Academic Journal
Venular oxygen saturation is increased in young patients with type 1 diabetes and mild nonproliferative diabetic retinopathy
| العنوان: | Venular oxygen saturation is increased in young patients with type 1 diabetes and mild nonproliferative diabetic retinopathy |
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| المؤلفون: | C.B.B. Veiby, Nina, Simeunovic, Aida, Heier, Martin, Brunborg, Cathrine, Saddique, Naila, Moe, Morten C., Dahl‐Jørgensen, Knut, Margeirsdottir, Hanna D., Petrovski, Goran |
| المساهمون: | The Norwegian Diabetes Association, The Dam Foundation, The Norwegian Association of the Blind and Partially Sighted, South-Eastern Norway Regional Health Authority |
| المصدر: | Acta Ophthalmologica ; volume 98, issue 8, page 800-807 ; ISSN 1755-375X 1755-3768 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2020 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Purpose To clarify how early in the development of diabetic retinopathy (DR) can oxygen (O 2 ) saturation changes be detected. Methods Retinal oximetry was performed in a cross‐sectional study, involving 14‐ to 30‐year‐old individuals: 185 with type 1 diabetes (T1D) and 94 controls. The subjects were divided into four groups according to the grade of DR. One‐way ANOVA and post hoc tests were used to test for differences in the mean O 2 saturations between the groups. Results Fifty‐eight (31 %) of the T1D patients had nonproliferative DR. There was no significant difference in O 2 saturations between controls and T1D patients with no DR. Arteriolar and venular O 2 saturations in T1D patients were significantly higher in moderate/severe DR than in no DR (p = 0.009 and p > 0.001), while venular O 2 saturation was significantly higher in mild DR than in no DR (p = 0.013). Conclusion Increase in venular O 2 saturation could not be detected before mild retinopathy had developed, and the retinal O 2 saturation increase was measurable on the venular side first. Our results suggest that the increase in O 2 saturation is likely a consequence of DR. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/aos.14462 |
| الاتاحة: | http://dx.doi.org/10.1111/aos.14462 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Faos.14462 https://onlinelibrary.wiley.com/doi/pdf/10.1111/aos.14462 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/aos.14462 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.9FC2A417 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/aos.14462 |
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