التفاصيل البيبلوغرافية
| العنوان: |
Soft tissue sarcoma incidences and clinical characteristics are significantly different in France and Taiwan. |
| المؤلفون: |
Chen, T. W., Chiang, R. C., Le Cesne, Alex, Hsieh, Y. C., Italiano, Antoine, Yang, Y. W., Penel, Nicolas, Lee, W. C., Bompas, Emmanuelle, Valentin, Thibaud, Anract, Philippe, Firmin, Nelly, Duffaud, Florence, Cheng, A. L., Ducimetiere, Françoise, Chan, K. A., Blay, Jean-Yves |
| المساهمون: |
Université de Lille, CHU Lille, Institut Gustave Roussy IGR, Institut Bergonié Bordeaux, METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694, Institut de Cancérologie de l'Ouest Angers/Nantes UNICANCER/ICO, Institut Universitaire du Cancer de Toulouse - Oncopole IUCT Oncopole - UMR 1037, Hôpital Cochin AP-HP, Institut régional de Cancérologie de Montpellier ICM, Hôpital de la Timone CHU - APHM TIMONE, Centre Léon Bérard Lyon |
| سنة النشر: |
2024 |
| المجموعة: |
LillOA (Lille Open Archive - Université de Lille) |
| مصطلحات موضوعية: |
epidemiology, ethnicity, geographical factors, sarcoma, soft tissue sarcoma |
| الوصف: |
Background The incidence of different soft tissue sarcoma (STS) histotypes among ethnic and geographic populations has not been comprehensively investigated. Methods Data from 2013 to 2016 were obtained from national cancer registry databases in France and Taiwan. Liposarcoma (LPS), leiomyosarcoma (LMS), angiosarcoma (AS), synovial sarcoma (SS), and malignant peripheral nerve sheath tumor (MPNST) were selected as index STSs to estimate the age-standardized incidence rates (ASRs) and other clinical features between patients. Results In total, 9398 patients (7148 from France and 2250 from Taiwan) were included. The ASRs of AS (5.4 vs. 2.8) and MPNST (2.0 vs. 1.0) were significantly higher in Taiwan; France had significantly higher ASRs for LPS (12.0 vs. 10.0), LMS (9.7 vs. 7.6), and SS (1.7 vs. 1.2). Patients in Taiwan with LMS or LPS were younger than their French counterparts. With regard to the distribution according to primary anatomic site, French patients had higher odds for extremity and truncal LMS (odds ratio [OR], 2.84; p < .001), AS (OR, 2.67; p < .001), MPNST (OR, 1.55; p = .027), and LPS (OR, 1.38; p < .001) and for breast AS (OR, 10.58; p < .001). Taiwanese patients had higher odds for liver AS (OR, 10.72; p < .001) and uterine LMS (OR, 3.21; p < .001). SS age and distribution according to primary anatomic site did not differ significantly between the French and Taiwanese populations. Conclusions Significant differences in the incidence and clinical characteristics of index STS suggested that geographic (environmental) and ethnicity factors likely play a vital role in the pathogenesis of STS. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/octet-stream |
| اللغة: |
English |
| تدمد: |
35796499 |
| Relation: |
Cancer; http://hdl.handle.net/20.500.12210/90038 |
| الاتاحة: |
https://hdl.handle.net/20.500.12210/90038 |
| رقم الانضمام: |
edsbas.9F02EA40 |
| قاعدة البيانات: |
BASE |