Academic Journal
Spectral analysis and biological activity assessment of silver doped hydroxyapatite
| العنوان: | Spectral analysis and biological activity assessment of silver doped hydroxyapatite |
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| المؤلفون: | Erdem, Ümit, Bozer, Büşra Moran, Türköz, Mustafa Burak, Metin, Ayşegül Ülkü, Yıldırım, Gürcan |
| المساهمون: | BAİBÜ, Mühendislik Fakültesi, Makine Mühendisliği Bölümü, orcid:0000-0002-0480-8176, orcid:0000-0002-7280-4417, orcid:0000-0002-4127-7650, orcid:0000-0001-8494-601X, orcid:0000-0002-5177-3703, Yıldırım, Gürcan |
| بيانات النشر: | TAYLOR & FRANCIS LTD |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Hydroxyapatite, Silver Doping, Biocompability, Cell Migration, Thin-Films, Antibacterial |
| الوصف: | In this study, the hydroxyapatite biomaterials are produced by the precipitation method and the role of silver doping within the different molar ratios of 2.0, 5.0, and 10.0% are investigated with some fundamental analysis, including powder XRD, SEM, EDS, FTIR, Raman, and material densities. In vitro biocompatibility assessment is conducted with cytotoxicity and agar diffusion tests. Moreover, genotoxicity tests determine whether the biomaterials produced cause the mutations or not. In addition, a hemolytic effect test examines the variation of hemolytic behavior of compounds. Also, the cell migration experiments inspect the influence of silver ion levels in biomaterials on many biological processes. The experimental results reveal that the honeycomb-patterned morphological structures are obtained for all the products. FTIR and Raman analyses reveal that the dramatic changes in the characteristic functional group peaks are obtained with the increment in the amount of silver ions. The experimental parts related to the biocompatibility assessment of the study show that there seems to be deterioration in biocompatibility as the silver ion-doping level increases in the system. To sum up, the ideal doping value for bone tissue engineering applications is found to be 2%. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2187-0764 |
| Relation: | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Journal of Asian Ceramic Societies; Erdem, U., Bozer, B. M., Turkoz, M. B., Metin, A. U., Yıldırım, G., Turk, M., & Nezir, S. (2021). Spectral analysis and biological activity assessment of silver doped hydroxyapatite. Journal of Asian Ceramic Societies, 9(4), 1524-1545.; http://dx.doi.org/10.1080/21870764.2021.1989749; https://hdl.handle.net/20.500.12491/11593; 1524; 1545 |
| DOI: | 10.1080/21870764.2021.1989749 |
| الاتاحة: | https://hdl.handle.net/20.500.12491/11593 https://doi.org/10.1080/21870764.2021.1989749 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.9E85F926 |
| قاعدة البيانات: | BASE |
| تدمد: | 21870764 |
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| DOI: | 10.1080/21870764.2021.1989749 |