Academic Journal
Reversible G1 arrest induced by dimethyl sulfoxide in human lymphoid cell lines: kinetics of the arrest and expression of the cell cycle marker proliferating cell nuclear antigen in Raji cells. Cell Growth Differ
| العنوان: | Reversible G1 arrest induced by dimethyl sulfoxide in human lymphoid cell lines: kinetics of the arrest and expression of the cell cycle marker proliferating cell nuclear antigen in Raji cells. Cell Growth Differ |
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| المؤلفون: | Kozo Takase, Masaji Sawai, Kohtaro Yamamoto, Jun-ichi Yata, Yoshinari Takasaki, Hirobumi Teraoka, Kinji Tsukada |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://cgd.aacrjournals.org/cgi/reprint/3/8/515.pdf. |
| سنة النشر: | 1992 |
| المجموعة: | CiteSeerX |
| الوصف: | In order to elucidate further the mechanism of reversible cell cycle arrest induced by treatment of Raji cells with 1.5 % dimethyl sulfoxide (DMSO), we have performed a detailed analysis of the kinetics of arrest and of reentry into the cell cycle after removal of DMSO and have correlated cell cycle progression with expression of proliferating cell nuclear antigen (PCNA). No significant effect of DMSO on cell cycle patterns, assessed by flow cytometric analysis of bromodeoxyuridine-prelabeled cells, was seen for the first 19 h of treatment. A clear reduction of entry into S phase was detected by about 25 h of treatment; essentially all cells were arrested with a G1 content of DNA after 96 h of treatment. When DMSO-arrested |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.514.7126; http://cgd.aacrjournals.org/cgi/reprint/3/8/515.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.514.7126 http://cgd.aacrjournals.org/cgi/reprint/3/8/515.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.9D023A19 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |