Academic Journal
Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy
| العنوان: | Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy |
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| المؤلفون: | Liew, Hui Shan, Mai, Chun-Wai, Zulkefeli, Mohd, Madheswaran, Thiagarajan, Kiew, Lik Voon, Delsuc, Nicolas, Low, May Lee |
| المساهمون: | International Medical University (IMU), Faculty of Medicine, University of Malaya Kuala Lumpur, Malaisie, University of Malaya = Universiti Malaya Kuala Lumpur, Malaisie (UM), Laboratoire des biomolécules (LBM UMR 7203), Chimie Moléculaire de Paris Centre (FR 2769), École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris Sciences et Lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris Sciences et Lettres (PSL)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Département de Chimie - ENS-PSL, Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Département de Chimie - ENS-PSL, Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL) |
| المصدر: | ISSN: 1420-3049 ; Molecules ; https://hal.sorbonne-universite.fr/hal-02988212 ; Molecules, 2020, 25 (18), pp.4176. ⟨10.3390/molecules25184176⟩. |
| بيانات النشر: | CCSD MDPI |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | cancer, medicinal inorganic chemistry, metals in medicine, photodynamic therapy, photosensitisers, rhenium(I) tricarbonyl complexes, [CHIM.COOR]Chemical Sciences/Coordination chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry |
| الوصف: | International audience ; Photodynamic therapy (PDT) is emerging as a significant complementary or alternative approach for cancer treatment. PDT drugs act as photosensitisers, which upon using appropriate wavelength light and in the presence of molecular oxygen, can lead to cell death. Herein, we reviewed the general characteristics of the different generation of photosensitisers. We also outlined the emergence of rhenium (Re) and more specifically, Re(I) tricarbonyl complexes as a new generation of metal-based photosensitisers for photodynamic therapy that are of great interest in multidisciplinary research. The photophysical properties and structures of Re(I) complexes discussed in this review are summarised to determine basic features and similarities among the structures that are important for their phototoxic activity and future investigations. We further examined the in vitro and in vivo efficacies of the Re(I) complexes that have been synthesised for anticancer purposes. We also discussed Re(I) complexes in conjunction with the advancement of two-photon PDT, drug combination study, nanomedicine, and photothermal therapy to overcome the limitation of such complexes, which generally absorb short wavelengths. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/32932573; PUBMED: 32932573; PUBMEDCENTRAL: PMC7571230 |
| DOI: | 10.3390/molecules25184176 |
| الاتاحة: | https://hal.sorbonne-universite.fr/hal-02988212 https://hal.sorbonne-universite.fr/hal-02988212v1/document https://hal.sorbonne-universite.fr/hal-02988212v1/file/molecules-25-04176.pdf https://doi.org/10.3390/molecules25184176 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.9C6E4963 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/molecules25184176 |
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