Academic Journal
Diabetic gastroparesis: current data on epidemiology, pathophysiology, diagnosis and treatment. Review ; Діабетичний гастропарез: сучасні дані щодо епідеміології, патофізіології, діагностики та лікування. Огляд літератури
| العنوان: | Diabetic gastroparesis: current data on epidemiology, pathophysiology, diagnosis and treatment. Review ; Діабетичний гастропарез: сучасні дані щодо епідеміології, патофізіології, діагностики та лікування. Огляд літератури |
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| المؤلفون: | Ткач, С. М., Паньків, В. І., Доготар, В. Б., Юзвенко, В. С. |
| المصدر: | Clinical Endocrinology and Endocrine Surgery; No. 3 (2022); 78-86 ; Clinical Endocrinology and Endocrine Surgery; № 3 (2022); 78-86 ; 2519-2582 ; 1818-1384 |
| بيانات النشر: | УНПЦЕХ, ТЕОіТ МОЗ України (URPCES, TEO&T of the Ministry of Health of Ukraine) |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | diabetes mellitus, diabetic gastroparesis, risk factors, diagnosis, treatment, цукровий діабет, діабетичний гастропарез, чинники ризику, діагностика, лікування |
| الوصف: | The analysis has been performed for the current data on the epidemiology, pathophysiology, diagnosis and treatment of diabetic gastroparesis. The search was conducted in PubMed and Medline databases. The following keywords were used: «diabetic gastroparesis», «complications of diabetes», «risk factors». Articles published in peer‑reviewed publications were taken into account. Diabetic gastroparesis is aserious complication of diabetes, which leads to its poor control, worsens the quality of life, increases frequency of comorbidities and mortality. This complication is characterized by abdominal distension, nausea, vomiting, weight loss and early satiety, but should be confirmed/diagnosed by scintigraphy or 13C‑octanoic breath test. Though there is no evidence that diabetic gastroparesis significantly increases mortality, this complication impairs all aspects of life. Gastroparesis carries asignificant burden on patients, with anegative correlation between the severity of symptoms and their quality of life; the disease also has asignificant negative impact on the health care system, in particular, due to increase in the number of hospitalizations and associated direct and indirect economic consequences. First‑line treatment for diabetic gastroparesis includes dietary modification, glycemic control, and fluid and electrolyte replacement. Those patients who have persistent symptoms may require pharmacological or even surgical treatment. Among pharmaceuticals, prokinetics are most often used, in particular metoclopramide, domperidone or erythromycin. Antiemetics, in particular phenothiazines and antihistamines, are also prescribed to reduce symptoms. Newer drugs under investigation include ghrelin agonists such as relamorelin, as well as serotonin receptor agonists such as prucalopride and velusetrag. In refractory cases, various options for surgical treatment or electrical stimulation of the stomach are recommended. ; Проаналізовано сучасні дані щодо епідеміології, патофізіології, діагностики та лікування ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Ukrainian |
| Relation: | http://jcees.endocenter.kiev.ua/article/view/265352/264555; http://jcees.endocenter.kiev.ua/article/view/265352 |
| DOI: | 10.30978/CEES-2022-3-78 |
| الاتاحة: | http://jcees.endocenter.kiev.ua/article/view/265352 https://doi.org/10.30978/CEES-2022-3-78 |
| Rights: | http://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.9B6B260A |
| قاعدة البيانات: | BASE |
| DOI: | 10.30978/CEES-2022-3-78 |
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