التفاصيل البيبلوغرافية
| العنوان: |
Differential splicing in response to CDK4/6 and PRMT5 inhibition. |
| المؤلفون: |
Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma , gene expression, alternative splicing |
| الوصف: |
(A) Types of alternative splicing events identified by rMATS. (B) Number of differentially spliced events and differentially spliced genes shared in CDK4/6 and PRMT5 inhibited samples. (C) Abundance of different types of splice events in CDK4/6 and PRMT5 inhibited samples. Exon inclusion level difference of skipped exons events detected across all samples, related to processed transcript (D) and protein coding (E) . |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Differential_splicing_in_response_to_CDK4_6_and_PRMT5_inhibition_/24489875 |
| DOI: |
10.1371/journal.pone.0292278.g003 |
| الاتاحة: |
https://doi.org/10.1371/journal.pone.0292278.g003
https://figshare.com/articles/figure/Differential_splicing_in_response_to_CDK4_6_and_PRMT5_inhibition_/24489875 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.9B5BF059 |
| قاعدة البيانات: |
BASE |