التفاصيل البيبلوغرافية
| العنوان: |
Crystal Structure Reveals the Binding Mode and Selectivity of a Photoswitchable Ligand for the Adenosine A2A Receptor |
| المؤلفون: |
Araya, Tsuyoshi, Matsuba, Yuya, Suzuki, Harufumi, Doura, Tomohiro, Nuemket, Nipawan, Nango, Eriko, Yamamoto, Masaki, Im, Dohyun, Asada, Hidetsugu, Kiyonaka, Shigeki, Iwata, So |
| بيانات النشر: |
American Chemical Society (ACS) |
| سنة النشر: |
2023 |
| الوصف: |
Rational synthetic expansion of photoresponsive ligands is important for photopharmacological studies. In this study, the photoresponsive and receptor-selective ligand, photoNECA(blue), was synthesized for the adenosine A2A receptor, and its crystal structure was determined. This complex structure explains the binding mode and photoresponsive mechanism of photoNECA(blue). |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| DOI: |
10.26434/chemrxiv-2023-7q2ht |
| الاتاحة: |
http://dx.doi.org/10.26434/chemrxiv-2023-7q2ht
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/651b9469a69febde9e207cee/original/crystal-structure-reveals-the-binding-mode-and-selectivity-of-a-photoswitchable-ligand-for-the-adenosine-a2a-receptor.pdf |
| Rights: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: |
edsbas.9AB5CBBE |
| قاعدة البيانات: |
BASE |