Academic Journal
Improvement of the diabetic foot upon testosterone administration to hypogonadal men with peripheral arterial disease. Report of three cases
| العنوان: | Improvement of the diabetic foot upon testosterone administration to hypogonadal men with peripheral arterial disease. Report of three cases |
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| المؤلفون: | Zemlyanoy Alexandr, Kalinchenko Svetlana, Gooren Louis J |
| المصدر: | Cardiovascular Diabetology, Vol 8, Iss 1, p 19 (2009) |
| بيانات النشر: | BMC |
| سنة النشر: | 2009 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Background Lower extremity complications (neuropathy, ulceration, infection, and peripheral arterial disease) are common in diabetes mellitus. There is an inverse relation between plasma testosterone and insulin sensitivity, type 2 diabetes mellitus and HbA1c concentrations. Methods We report the beneficial effects of administration of testosterone to three men with a diabetic foot whose serum testosterone was subnormal. Results Upon normalization of serum testosterone there was an improvement of hyperglycemia, a decrease of leukocytes and of fibrinogen levels, an increase of antithrombin III activity and of tissue oxygen pressure. The wound showed granulation. Conclusion Beneficial effects of administration of testosterone to hypogonadal with a diabetic foot may be due to improved vascularization and to anti-inflammatory action. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1475-2840 |
| Relation: | http://www.cardiab.com/content/8/1/19; https://doaj.org/toc/1475-2840; https://doaj.org/article/3d2e26e80e154e5bb15d21ccd8597c33 |
| DOI: | 10.1186/1475-2840-8-19 |
| الاتاحة: | https://doi.org/10.1186/1475-2840-8-19 https://doaj.org/article/3d2e26e80e154e5bb15d21ccd8597c33 |
| رقم الانضمام: | edsbas.99D23FFC |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14752840 |
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| DOI: | 10.1186/1475-2840-8-19 |