التفاصيل البيبلوغرافية
| العنوان: |
Bixasteroid, a new compound from the fruits of Bixa orellana and its anti-inflammatory activity |
| المؤلفون: |
Yi-min Chen (9276782), Tian-qi Xu (9276776), Xiao-qi Zhang (3425900), Chun-lin Fan (11421165), Wen-cai Ye (3508565), Wei Xu (28953), Guang-xiong Zhou (5320127) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Pharmacology, Ecology, Sociology, Immunology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Bixa orellana, X-ray diffraction, anti-inflammatory activity, ECD calculations, bixasteroid |
| الوصف: |
Bixasteroid ( 1 ), one new steroid together with five known compounds ( 2 – 6 ), were isolated from the ethyl acetate fraction of ethanol extract of Bixa orellana fruits. All of these known compounds were isolated from the plant for the first time. Their structures were elucidated on the basis of spectroscopic analysis, and the absolute configuration of compound 1 was determined by X-ray crystallographic data analysis as well as by the quantum chemical ECD calculations. All the isolated compounds were tested for their anti-inflammatory activities. Compounds 1 and 2 showed inhibiting NO release activities in LPS-induced RAW 264.7 macrophages with the IC 50 values of 4.72 ± 0.28 and 5.48 ± 1.48 μ M, respectively. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Bixasteroid_a_new_compound_from_the_fruits_of_i_Bixa_orellana_i_and_its_anti-inflammatory_activity/16607214 |
| DOI: |
10.6084/m9.figshare.16607214.v1 |
| الاتاحة: |
https://doi.org/10.6084/m9.figshare.16607214.v1 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.99BC4DEE |
| قاعدة البيانات: |
BASE |