Academic Journal
New developments in HIV drug resistance
| العنوان: | New developments in HIV drug resistance |
|---|---|
| المؤلفون: | Patricia A. Cane |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://jac.oxfordjournals.org/content/64/suppl_1/i37.full.pdf. |
| سنة النشر: | 2009 |
| المجموعة: | CiteSeerX |
| مصطلحات موضوعية: | new drugs, tropism determination, minority mutant detection, dried blood spots |
| الوصف: | Several new antiretroviral drugs have recently been licensed for use in HIV-1-infected patients. These include drugs in two new classes: an integrase inhibitor (raltegravir) and a CCR5 co-receptor antagon-ist (maraviroc). In addition, two new protease inhibitors, atazanavir and darunavir, which have activity against viruses resistant to other protease inhibitors, have come into clinical use. Finally etravirine, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) is being increasingly used in patients whose virus is resistant to the earlier NNRTIs. These clinical advances have required the development of novel assays and interpretation systems for detection of resistance to allow the laboratory monitor-ing of patients receiving these new therapies. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.8212; http://jac.oxfordjournals.org/content/64/suppl_1/i37.full.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.526.8212 http://jac.oxfordjournals.org/content/64/suppl_1/i37.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.9747B85A |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |