التفاصيل البيبلوغرافية
| العنوان: |
First detection of anthrax biomarkers. |
| المؤلفون: |
Anne E. Boyer (237019), Maribel Gallegos-Candela (330909), Renato C. Lins (14279454), Maria I. Solano (14279457), Adrian R. Woolfitt (2467474), John S. Lee (446566), Daniel C. Sanford (2141863), Katherine A. B. Knostman (14279460), Conrad. P. Quinn (14279463), Alex R. Hoffmaster (7349129), James L. Pirkle (17765), John R. Barr (71845) |
| سنة النشر: |
2022 |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Microbiology, Molecular Biology, Cancer, Statistics, Science Policy, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, three toxemic phases, three clinical stages, shorter survival times, one animal survived, mean &# 177, lower &# 8211, longer survival times, 9 &# 8211, 9 &# 177, 113 &# 177, first comprehensive evaluation, 6 &# 8211, 5 &# 177, pa ), 8 &# 177, 7 &# 177, 23 cynomolgus macaques, lf levels across, final rapid rise |
| Time: |
35 |
| الوصف: |
First detection of biomarkers relative to symptom onset in 23 cynomolgus macaques with inhalation anthrax. Pre-symptom onset period (gray bar) and post-symptom onset period (blue bar) out to 144 hours, for total lethal factor (LF), total edema factor (EF), total protective antigen (PA), and confirmed bacteremia. Detection limits for LF (0.0027 ng/mL), EF (0.00002 ng/mL), PA (1.87 ng/mL) and confirmed bacteremia (≥100 cfu/mL). Non-confirmed results of ‘+’ excluded here but included in Table 2 . |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/First_detection_of_anthrax_biomarkers_/21753060 |
| DOI: |
10.1371/journal.ppat.1010735.g001 |
| الاتاحة: |
https://doi.org/10.1371/journal.ppat.1010735.g001 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.96799E11 |
| قاعدة البيانات: |
BASE |