Academic Journal

Evaluation of three commercially-available chikungunya virus immunoglobulin G immunoassays

التفاصيل البيبلوغرافية
العنوان: Evaluation of three commercially-available chikungunya virus immunoglobulin G immunoassays
المؤلفون: Pablo M. De Salazar, Anne Marie Valadere, Christin H. Goodman, Barbara W. Johnson
المصدر: Revista Panamericana de Salud Pública, Vol 41, Iss 0 (2017)
بيانات النشر: Pan American Health Organization
سنة النشر: 2017
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: Virus chikungunya, juego de reactivos para diagnóstico, diagnostic, inmunoensayo, técnicas para inmunoenzimas, inmunoensayo de polarización fluorescente, Región del Caribe, Américas, Medicine, Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270
الوصف: The emergence of chikungunya virus in the Americas means the affected population is at risk of developing severe, chronic, rheumatologic disease, even months after acute infection. Accurate diagnostic methods for past infections are essential for differential diagnosis and consequence management. This study evaluated three commercially-available chikungunya Immunoglobulin G immunoassays by comparing them to an in-house Enzyme-Linked ImmunoSorbent Assay conducted by the Centers for Disease Control and Prevention (Atlanta, Georgia, United States). Results showed sensitivity and specificity values ranging from 92.8% – 100% and 81.8% – 90.9%, respectively, with a significant number of false-positives ranging from 12.5% – 22%. These findings demonstrate the importance of evaluating commercial kits, especially regarding emerging infectious diseases whose medium and long-term impact on the population is unclear.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Spanish; Castilian
Portuguese
تدمد: 1680-5348
Relation: http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892017000100408&lng=en&tlng=en; https://doaj.org/toc/1680-5348; https://doaj.org/article/8e77f9c52eea478b88b70232934e32d8
الاتاحة: https://doaj.org/article/8e77f9c52eea478b88b70232934e32d8
رقم الانضمام: edsbas.96376617
قاعدة البيانات: BASE