Academic Journal
Clinical implication of the Naples prognostic score on transcatheter aortic valve replacement in patients with severe aortic stenosis
| العنوان: | Clinical implication of the Naples prognostic score on transcatheter aortic valve replacement in patients with severe aortic stenosis |
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| المؤلفون: | Demirci, Gökhan, Aslan, Serkan, Güner, Ahmet, Demir, Ali R., Erata, Yunus E., Türkmen, İrem, Yalçın, Ahmet A., Kalkan, Ali K., Uzun, Fatih, Çelik, Ömer, Ertürk, Mehmet |
| المصدر: | Catheterization and Cardiovascular Interventions ; volume 103, issue 1, page 219-225 ; ISSN 1522-1946 1522-726X |
| بيانات النشر: | Wiley |
| سنة النشر: | 2023 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Background One of the hallmarks of frailty in patients with severe aortic stenosis (AS) is malnutrition, for which one of the most up‐to‐date scoring systems is the Naples prognostic score (NPS). This study sought to investigate the predictive role of the NPS in determining mortality in patients undergoing transcatheter aortic valve replacement (TAVR) under long‐term follow‐up. Methods A total of 430 consecutive patients with symptomatic severe AS who underwent TAVR were included retrospectively. The primary endpoint of the study was the long‐term all‐cause mortality. The study population was divided into two groups according to the NPS value, including Group 1 (NPS 0–2) and Group 2 (NPS 3–4). Results The all‐cause mortality occurred in 250 patients (62.5%) patients during a follow‐up time of 40.6 (22.0–69.4) months. During the follow‐up period, all‐cause mortality was higher in Group 2 compared with Group 1 (87.9% vs. 42.9%, p < 0.001). Older age ( p < 0.001), chronic obstructive pulmonary disease ( p = 0.015), left ventricular ejection fraction ( p = 0.021), and being in Group 2 (high NPS) (hazard ratio: 7.058, 95% confidence interval: 5.174–9.629, p < 0.001) were found to be independent predictors of all‐cause mortality at long‐term follow‐up. Conclusion The NPS as a malnutrition and inflammation marker in patients with severe aortic stenosis who underwent TAVR provides valuable information for all‐cause mortality under long‐term follow‐up. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/ccd.30929 |
| الاتاحة: | http://dx.doi.org/10.1002/ccd.30929 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccd.30929 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.95F7839D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/ccd.30929 |
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