Academic Journal
Total Dairy Consumption Is Not Associated With Likelihood of a First Clinical Diagnosis of Central Nervous System Demyelination
| العنوان: | Total Dairy Consumption Is Not Associated With Likelihood of a First Clinical Diagnosis of Central Nervous System Demyelination |
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| المؤلفون: | Dieu, Dao Ying Rachel, Dunlop, Eleanor, Daly, Alison, Lucas, Robyn M., Probst, Yasmine, Black, Lucinda J. |
| المساهمون: | National Multiple Sclerosis Society, National Health and Medical Research Council, Multiple Sclerosis Research Australia, Multiple Sclerosis Society of Western Australia |
| المصدر: | Frontiers in Neurology ; volume 13 ; ISSN 1664-2295 |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2022 |
| المجموعة: | Frontiers (Publisher - via CrossRef) |
| الوصف: | Background The evidence associating consumption of dairy products and risk of MS is contradictory and inconclusive. Objective To test associations between dairy consumption and the likelihood of a first clinical diagnosis of central nervous system demyelination (FCD), a common precursor to MS. Methods We used data from the 2003–2006 Ausimmune Study, a population-based Australian, multicentre, matched case-control study (272 cases, 519 controls). Total dairy consumption (servings/day) was calculated by summing consumption of milk, cheese and yogurt. Covariate-adjusted treatment effects using augmented inverse probability weighting was used to test for associations with FCD. We conducted sensitivity analyses in the subset of participants who had had a classic first demyelinating event (FDE), defined as a single, first episode of symptoms suggestive of CNS demyelination. Results There were no statistically significant associations between total dairy consumption (per one serving/day) and FCD (adjusted OR 1.00; 95% CI 0.93, 1.07; p = 0.979). However, yogurt consumption (vs. no yogurt consumption) was associated with an 11% decreased likelihood of FDE (adjusted OR 0.89; 95% CI 0.89, 0.79; p = 0.046). Conclusion While total dairy consumption was not associated with FCD in this Australian case-control study, yogurt consumption was associated with reduced likelihood of FDE. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| DOI: | 10.3389/fneur.2022.888559 |
| DOI: | 10.3389/fneur.2022.888559/full |
| الاتاحة: | http://dx.doi.org/10.3389/fneur.2022.888559 https://www.frontiersin.org/articles/10.3389/fneur.2022.888559/full |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.9557BDF9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fneur.2022.888559 |
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