التفاصيل البيبلوغرافية
| العنوان: |
Data from: Optogenetic dissection of descending behavioral control in Drosophila |
| المؤلفون: |
Cande, Jessica, Namiki, Shigehiro, Qiu, Jirui, Korff, Wyatt, Card, Gwyneth M., Shaevitz, Joshua W., Stern, David L., Berman, Gordon J. |
| بيانات النشر: |
Zenodo |
| سنة النشر: |
2019 |
| المجموعة: |
Zenodo |
| مصطلحات موضوعية: |
Drosophila melanoagster, descending neurons, optogenetics |
| الوصف: |
In most animals, the brain makes behavioral decisions that are transmitted by descending neurons to the nerve cord circuitry that produces behaviors. In insects, only a few descending neurons have been associated with specific behaviors. To explore how descending neurons control an insect's movements, we developed a novel method to systematically assay the behavioral effects of activating individual neurons on freely behaving terrestrial D. melanogaster. We calculated a two-dimensional representation of the entire behavior space explored by these flies and we associated descending neurons with specific behaviors by identifying regions of this space that were visited with increased frequency during optogenetic activation. Applying this approach across a large collection of descending neurons, we found that (1) activation of most of the descending neurons drove stereotyped behaviors, (2) in many cases multiple descending neurons activated similar behaviors, and (3) optogenetically-activated behaviors were often dependent on the behavioral state prior to activation. ; Movies of optogenetically activated split-Gal4 lines Each movie contains 1 second before and after optogenetic stimulation for all experimental (retinal +) and control (retinal -) flies for all stimulation trials. opto_movies.zip |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| Relation: |
https://doi.org/10.7554/elife.34275; https://zenodo.org/communities/dryad; https://doi.org/10.5061/dryad.fr89c0c; oai:zenodo.org:4999893 |
| DOI: |
10.5061/dryad.fr89c0c |
| الاتاحة: |
https://doi.org/10.5061/dryad.fr89c0c |
| Rights: |
info:eu-repo/semantics/openAccess ; Creative Commons Zero v1.0 Universal ; https://creativecommons.org/publicdomain/zero/1.0/legalcode |
| رقم الانضمام: |
edsbas.9534E37E |
| قاعدة البيانات: |
BASE |