التفاصيل البيبلوغرافية
| العنوان: |
Deciphering tissue-specific regulation and contribution of transposable elements to cis-regulatory sequences |
| المؤلفون: |
Maud, Fagny, Marieke L., Kuijer, Maike, Stam, Johann, Joets, Olivier, Turc, Julien, Rozière, Stéphanie, Pateyron, Anthony, Venon, Clémentine, Vitte |
| المساهمون: |
Génétique Quantitative et Evolution - Le Moulon (Génétique Végétale) (GQE-Le Moulon), AgroParisTech-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre for Molecular Medicine Norway (NCMM), Faculty of Medicine Oslo, University of Oslo (UiO)-University of Oslo (UiO)-Rigshospitalet Copenhagen, Copenhagen University Hospital-Copenhagen University Hospital, University of Oslo (UiO), Swammerdam Institute for Life Sciences (SILS), University of Amsterdam Amsterdam = Universiteit van Amsterdam (UvA), Écophysiologie des Plantes sous Stress environnementaux (LEPSE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut des Sciences des Plantes de Paris-Saclay (IPS2 (UMR_9213 / UMR_1403)), Université d'Évry-Val-d'Essonne (UEVE)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), ANR-10-BTBR-0001,AMAIZING,Développer de nouvelles variétés de maïs pour une agriculture durable: une approche intégrée de la génomique à la sélection(2010) |
| المصدر: |
Epiplant III ; https://hal.science/hal-04351579 ; Epiplant III, Feb 2021, Visio conference, France |
| بيانات النشر: |
CCSD |
| سنة النشر: |
2021 |
| مصطلحات موضوعية: |
Gene regulatory network, Transposable elements, Enhancer, Maize, [SDV]Life Sciences [q-bio] |
| جغرافية الموضوع: |
Visio conference, France |
| Time: |
Visio conference, France |
| الوصف: |
International audience ; Maize, like many other crops, has a large genome size, and a large portion of its genome is filled with transposable elements. Recent analysis of distal cis-regulatory regions (dCREs) has revealed that the dCRE-gene distance peaks at 60kb in this species. Moreover, 3D chromatin folding analyses showed that about 25%-40% of dCREs are not targeting their closest gene, and that 34% of dCREs potentially regulate several genes. This highlights the difficulty to identify the regulatory relationships between dCREs and their target genes in maize. I will present recent results showing the power of systems biology to connect dCREs and corresponding transcription factors to their target genes in maize, and to decipher the regulatory modules underlying leaf tissue-specificity, together with their biological functions. How dCREs arise and rewire the gene regulatory network in plants is unclear. Transposable Elements (TEs) of various superfamilies have been proposed as a source of new regulatory elements in plants and animals. But whether TEs contribute to the emergence of tissue-specific gene regulatory networks in plants remains to be fully elucidated. I will show that TEs participate in shaping tissue-specific networks in maize, and that some have provided potential new transcription factor binding sites involved in leaf tissue-specificity. |
| نوع الوثيقة: |
conference object |
| اللغة: |
English |
| الاتاحة: |
https://hal.science/hal-04351579 |
| رقم الانضمام: |
edsbas.95143CE4 |
| قاعدة البيانات: |
BASE |