Academic Journal
Experimental mycobacteriosis in striped bass Morone saxatilis
| العنوان: | Experimental mycobacteriosis in striped bass Morone saxatilis |
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| المؤلفون: | Gauthier, DT, Rhodes, MW, Vogelbein, Wolfgang K., Kator, H, Ottinger, CA |
| المصدر: | VIMS Articles |
| بيانات النشر: | W&M ScholarWorks |
| سنة النشر: | 2003 |
| المجموعة: | College of William |
| مصطلحات موضوعية: | Aquatic Health Sciences Peer-Reviewed Articles, Aquaculture and Fisheries |
| الوصف: | Striped bass Morone saxatilis were infected intraperitoneally with approximately 10(5) Mycobacterium marinum, M. shottsii sp. nov., or M. gordonae. Infected fish were maintained in a flow-through freshwater system at 18 to 21degreesC, and were examined histologically and bacteriologically at 2, 4, 6, 8, 17, 26, 36 and 45 wk post-infection (p.i.). M. marinum caused acute peritonitis, followed by extensive granuloma development in the mesenteries, spleen and anterior kidney. Granulomas in these tissues underwent a temporal progression of distinct morphological stages, culminating in well-circumscribed lesions surrounded by normal or healing tissue. Mycobacteria were cultured in high numbers from splenic tissue at all times p.i. Standard Ziehl-Neelsen staining, however, did not demonstrate acid-fast rods in most early inflammatory foci and granulomas. Large numbers of acid-fast rods were present in granulomas beginning at 8 wk p.i. Between 26 and 45 wk p.i., reactivation of disease was observed in some fish, with disintegration of granulomas, renewed inflammation, and elevated splenic bacterial densities approaching 10(9) colony-forming units g(-1). Infection with M. shottsii or M. gordonae did not produce severe pathology. Mild peritonitis was followed by granuloma formation in the mesenteries, but, with 1 exception, granulomas were not observed in the spleen or anterior kidney. M. shottsii and M. gordonae both established persistent infections in the spleen, but were present at densities at least 2 orders of magnitude less than M marinum at all time points observed. Granulomas in the mesenteries of M shottsii- and M. gordonae-infected fish resolved over time, and no reactivation of disease was observed. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| Relation: | https://scholarworks.wm.edu/vimsarticles/1620; https://scholarworks.wm.edu/context/vimsarticles/article/2621/viewcontent/gauthier2003.pdf |
| DOI: | 10.3354/dao054105 |
| الاتاحة: | https://scholarworks.wm.edu/vimsarticles/1620 https://scholarworks.wm.edu/context/vimsarticles/article/2621/viewcontent/gauthier2003.pdf |
| رقم الانضمام: | edsbas.945D7821 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3354/dao054105 |
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