Academic Journal
The Role of the Sucrose-Responsive IR60b Neuron for Drosophila melanogaster : A Hypothesis
| العنوان: | The Role of the Sucrose-Responsive IR60b Neuron for Drosophila melanogaster : A Hypothesis |
|---|---|
| المؤلفون: | Szyszka, Paul, Galizia, C. Giovanni |
| المصدر: | Chemical Senses. 2018, 43(5), pp. 311-312. ISSN 0379-864X. eISSN 1464-3553. Available under: doi:10.1093/chemse/bjy020 |
| سنة النشر: | 2018 |
| المجموعة: | University of Konstanz: Konstanz Online Publication Server (KOPS) |
| مصطلحات موضوعية: | insects, nutrition, obesity, sugar sensing, taste receptor, ddc:570 |
| الوصف: | In a recent paper, Joseph and colleagues (Joseph et al. 2017) have characterized an IR60b receptor-expressing neuron in Drosophila. They showed that it responds to sucrose and serves to limit sucrose consumption, and proposed that it may thereby act to prevent overfeeding. Here, we propose an alternative hypothesis for the functional role of sucrose feeding control, and for how this limitation of sucrose uptake is accomplished. Adult fruit flies feed by excreting saliva onto the food, and imbibing the predigested liquefied food, or by filling the crop, where the food is predigested. Enzymes in the saliva hydrolyze starch and disaccharides into absorbable monosaccharides. Premature ingestion into the midgut would not give the enzymes in the saliva enough time to predigest the food. Thus, IR60b neurons might serve as a sensor to monitor the digestive state of external food or crop content: when disaccharides (sucrose) concentration is high, ingestion to the gut is inhibited, keeping a low concentration of starch and disaccharides in the midgut. ; published ; published |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1k1p4zmuiyl6z1; http://dx.doi.org/10.1093/chemse/bjy020; 506416003 |
| DOI: | 10.1093/chemse/bjy020 |
| الاتاحة: | http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1k1p4zmuiyl6z1 https://doi.org/10.1093/chemse/bjy020 |
| Rights: | http://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.942CA75B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/chemse/bjy020 |
|---|