التفاصيل البيبلوغرافية
العنوان: |
Effect of exercise therapy on lipid profile and oxidative stress indicators in patients with type 2 diabetes |
المؤلفون: |
Gordon, Lorenzo A, Morrison, Errol Y, McGrowder, Donovan A, Young, Ronald, Fraser, Yeiny, Zamora, Eslaen, Alexander-Lindo, Ruby L, Irving, Rachael R |
بيانات النشر: |
BioMed Central Ltd. |
سنة النشر: |
2008 |
المجموعة: |
BioMed Central |
الوصف: |
Background Yoga has been shown to be a simple and economical therapeutic modality that may be considered as a beneficial adjuvant for type 2 diabetes mellitus. This study investigated the impact of Hatha yoga and conventional physical training (PT) exercise regimens on biochemical, oxidative stress indicators and oxidant status in patients with type 2 diabetes. Methods This prospective randomized study consisted of 77 type 2 diabetic patients in the Hatha yoga exercise group that were matched with a similar number of type 2 diabetic patients in the conventional PT exercise and control groups. Biochemical parameters such as fasting blood glucose (FBG), serum total cholesterol (TC), triglycerides, low-density lipoprotein (LDL), very low-density lipoproteins (VLDL) and high-density lipoprotein (HDL) were determined at baseline and at two consecutive three monthly intervals. The oxidative stress indicators (malondialdehyde – MDA, protein oxidation – POX, phospholipase A2 – PLA2 activity) and oxidative status [superoxide dismutase (SOD) and catalase activities] were measured. Results The concentrations of FBG in the Hatha yoga and conventional PT exercise groups after six months decreased by 29.48% and 27.43% respectively (P < 0.0001) and there was a significant reduction in serum TC in both groups (P < 0.0001). The concentrations of VLDL in the managed groups after six months differed significantly from baseline values (P = 0.036). Lipid peroxidation as indicated by MDA significantly decreased by 19.9% and 18.1% in the Hatha yoga and conventional PT exercise groups respectively (P < 0.0001); whilst the activity of SOD significantly increased by 24.08% and 20.18% respectively (P = 0.031). There was no significant difference in the baseline and 6 months activities of PLA2 and catalase after six months although the latter increased by 13.68% and 13.19% in the Hatha yoga and conventional PT exercise groups respectively (P = 0.144). Conclusion The study demonstrate the efficacy of Hatha yoga exercise on ... |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
Relation: |
http://www.biomedcentral.com/1472-6882/8/21 |
الاتاحة: |
http://www.biomedcentral.com/1472-6882/8/21 |
Rights: |
Copyright 2008 Gordon et al; licensee BioMed Central Ltd. |
رقم الانضمام: |
edsbas.93B47DAD |
قاعدة البيانات: |
BASE |