Academic Journal
Tunnel excavation triggering pulmonary sarcoidosis
| العنوان: | Tunnel excavation triggering pulmonary sarcoidosis |
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| المؤلفون: | Kawano-Dourado, L. B., Carvalho, C. R. R., Santos, U. P., Canzian, M., Coletta, E. N. A. UNIFESP, Pereira, C. A. C. UNIFESP, Kairalla, R. A. |
| المساهمون: | Universidade de São Paulo (USP), Universidade Federal de São Paulo (UNIFESP) |
| بيانات النشر: | Wiley-Blackwell |
| سنة النشر: | 2012 |
| المجموعة: | Universidade Federal de São Paulo (UNIFESP): Repositório Institucional |
| مصطلحات موضوعية: | sarcoidosis, sarcoid-like lung disease, environmental, occupational, tunnel excavation |
| الوصف: | Context A definite cause of sarcoidosis has not been identified, however past research suggests that environmental factors may be triggers of the granulomatous response in genetically susceptible individuals. Case Presentation A 22-year-old male non-smoker, presented with progressive exertional dyspnea and cough of 3 months duration. One year before, when he started working in tunnel excavation, he had a normal chest radiograph. Chest imaging revealed bilateral nodules and masses of peribronchovascular distribution plus mediastinal lymphadenomegaly. Histologic lymph node analysis revealed non-caseating confluent granulomas. Sarcoidosis was diagnosed. the patient was treated with corticosteroids and advised to change jobs. Complete remission of the disease was achieved and persisted for at least one year without steroid treatment. Discussion Sarcoidosis is believed to have environmental triggers. the timing of the onset of sarcoidosis in this patient following intensive exposure to tunnel dust suggests an environmental contribution. the recognition that sarcoidosis may have occupational triggers have medical, employment, and legal implications. Am. J. Ind. Med. 55: 390-394, 2012. (C) 2011 Wiley Periodicals, Inc. ; Univ São Paulo FMUSP, Div Pulm, Heart Inst InCor, Sch Med, São Paulo, Brazil ; Univ São Paulo FMUSP, Div Pathol, Heart Inst InCor, Sch Med, São Paulo, Brazil ; Fed Univ São Paulo UNIFESP, Div Pathol, Sch Med, São Paulo, Brazil ; Fed Univ São Paulo UNIFESP, Div Pulm, Sch Med, São Paulo, Brazil ; Fed Univ São Paulo UNIFESP, Div Pathol, Sch Med, São Paulo, Brazil ; Fed Univ São Paulo UNIFESP, Div Pulm, Sch Med, São Paulo, Brazil ; Web of Science |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 390-394 |
| اللغة: | English |
| تدمد: | 0271-3586 |
| Relation: | American Journal of Industrial Medicine; http://dx.doi.org/10.1002/ajim.21030; American Journal of Industrial Medicine. Malden: Wiley-Blackwell, v. 55, n. 4, p. 390-394, 2012.; http://repositorio.unifesp.br/handle/11600/34739; WOS:000301483200010 |
| DOI: | 10.1002/ajim.21030 |
| الاتاحة: | http://repositorio.unifesp.br/handle/11600/34739 https://doi.org/10.1002/ajim.21030 |
| Rights: | Acesso restrito ; http://olabout.wiley.com/WileyCDA/Section/id-406071.html |
| رقم الانضمام: | edsbas.92CCDCD8 |
| قاعدة البيانات: | BASE |
| تدمد: | 02713586 |
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| DOI: | 10.1002/ajim.21030 |