Academic Journal
Reverse cardiac remodelling and dysfunction in A97S transthyretin cardiac amyloidosis after tafamidis treatment
| العنوان: | Reverse cardiac remodelling and dysfunction in A97S transthyretin cardiac amyloidosis after tafamidis treatment |
|---|---|
| المؤلفون: | Wu, Yuan‐Kun (Aden), Tsai, Cheng‐Hsuan, Su, Mao‐Yuan, Chao, Chi‐Chao, Cheng, Mei‐Fang, Shun, Chia‐Tung, Hsieh, Sung‐Tsang, Lin, Yen‐Hung |
| المصدر: | ESC Heart Failure ; volume 9, issue 6, page 4335-4339 ; ISSN 2055-5822 2055-5822 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2022 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Transthyretin cardiomyopathy (ATTR‐CM) is an under‐recognized cause of heart failure, but it has received increasing attention due to the availability of treatment options. We present a case of hereditary transthyretin cardiomyopathy (A97S, an under‐represented variant in current clinical studies) who presented with heart failure. Timely diagnosis and intervention with tafamidis demonstrated reversed cardiac remodelling via multiple imaging techniques (echocardiography, cardiac magnetic resonance imaging and technetium‐99m pyrophosphate scintigraphy). The echocardiography and cardiac magnetic resonance imaging demonstrated improved global strain. Cardiac magnetic resonance imaging showed decreased extracellular volume. The technetium‐99m pyrophosphate scintigraphy demonstrated decreased heart‐to‐contralateral ratio. This case highlights the potential reversible effect of tafamidis on A97S amyloidosis cardiomyopathy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/ehf2.14165 |
| الاتاحة: | http://dx.doi.org/10.1002/ehf2.14165 https://onlinelibrary.wiley.com/doi/pdf/10.1002/ehf2.14165 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ehf2.14165 |
| Rights: | http://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.92166E37 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/ehf2.14165 |
|---|