Academic Journal
V-A ECMO window of opportunity: identification of potential responders after an acute myocardial infarction complicated by cardiogenic shock
| العنوان: | V-A ECMO window of opportunity: identification of potential responders after an acute myocardial infarction complicated by cardiogenic shock |
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| المؤلفون: | Martinez Guisado, A, Andrea Riba, R, Roca Guerrero, C, Rodriguez Eguren, A, Cubells, M, De Diego, O, Ortiz, J T, Sabate Tenas, M, Lopez Sobrino, T |
| المصدر: | European Heart Journal: Acute Cardiovascular Care ; volume 13, issue Supplement_1 ; ISSN 2048-8726 2048-8734 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2024 |
| الوصف: | Funding Acknowledgements None. Background V-A ECMO is designed to supply oxygen demands in patients with circulatory failure. Neutral results obtained in recent cardiogenic shock (CS) trials are probably related to the inclusion of a high proportion of patients with SCAI C stage, in many of whom, the device might not provide hemodynamic benefit despite the addition of inherent complications. Mechanical circulatory support could potentially have a role only for patients in SCAI D-E stages. Purpose Our aim was to explore the excess in mortality explained by a SCAI D-E stage at 12h, compared to a SCAI A-C stages at 12h, in patients admitted due to an acute myocardial infarction (AMI) complicated by CS (stages C-E at admission). Additionally, we aimed to identify those factors at admission—clinical, electrocardiographic, gasometrical, echocardiographic, and angiographic—which predict whether a patient will progress to SCAI D-E stages within the subsequent 12h from CS onset. Main Outcome: SCAI D and E stage at 12h. Methods We retrospectively analysed those patients admitted due to an AMI in SCAI C-E stages at admission, that had been prospectively screened for EUROSHOCK trial. We classified the patients in two groups: "SCAI A-C" and "SCAI D-E" at 12 hours and conducted a survival analysis. Additionally, we conducted a univariate and multivariate analysis including arrival potential predictors for SCAI D-E at 12 hours. Results A total of 72 patients were included. At admission 25 patien were in SCAI D-E. At 12 hours, 42 patients were in SCAI D-E, and this group showed a higher 30-day mortality rate particularly explained by an excess of mortality within the first 7 days (Figure 1). There were no significant differences between groups in most baseline characteristics (Table 1) such as age or gender. We observed a fewer proportion of previous chronic treatment with negative inotropes (betablockers and calcium channel antagonists) in the SCAI D-E group. Overall, anterior ST elevation on EKG was more prevalent ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/ehjacc/zuae036.162 |
| الاتاحة: | http://dx.doi.org/10.1093/ehjacc/zuae036.162 https://academic.oup.com/ehjacc/article-pdf/13/Supplement_1/zuae036.162/57438276/zuae036.162.pdf |
| Rights: | https://academic.oup.com/pages/standard-publication-reuse-rights |
| رقم الانضمام: | edsbas.91E4E3F8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ehjacc/zuae036.162 |
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