Academic Journal
Pharmacokinetics and Pharmacodynamics of Inhaled versus Intravenous Morphine in Healthy Volunteers
| العنوان: | Pharmacokinetics and Pharmacodynamics of Inhaled versus Intravenous Morphine in Healthy Volunteers |
|---|---|
| المؤلفون: | Mark Dershwitz, Ph. D, John L. Walsh, Richard J. Morishige, Patricia M. Connors, Reid M. Rubsamen, I Steven L. Shafer, Carl E. Rosow |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://respira.com.mx/docs/f1267641013-0.pdf. |
| سنة النشر: | 2000 |
| المجموعة: | CiteSeerX |
| الوصف: | Background: A new pulmonary drug delivery system pro-duces aerosols from disposable packets of medication. This study compared the pharmacokinetics and pharmacodynamics of morphine delivered by an AERx prototype with intravenous morphine. Methods: Fifteen healthy volunteers were enrolled. Two sub-jects were administered four inhalations of 2.2 mg morphine each at 1-min intervals or 4.4 mg over 3 min by intravenous infusion. Thirteen subjects were given twice the above doses, i.e., eight inhalations or 8.8 mg intravenously over 7 min. Arte-rial blood sampling was performed every minute during admin- |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.458.2599; http://respira.com.mx/docs/f1267641013-0.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.458.2599 http://respira.com.mx/docs/f1267641013-0.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.91B9425B |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |