Academic Journal
Antenatal findings and early postnatal outcomes in pregnancies with trisomy 21: a 10 year retrospective review at a tertiary centre
| العنوان: | Antenatal findings and early postnatal outcomes in pregnancies with trisomy 21: a 10 year retrospective review at a tertiary centre |
|---|---|
| المؤلفون: | Stott, D, Dos Santos, F, Rodgers, A, Holgado, E, Pandya, PP |
| المصدر: | Prenatal Diagnosis , 42 (10) pp. 1273-1280. (2022) |
| بيانات النشر: | Wiley |
| سنة النشر: | 2022 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | Birth Weight, Cesarean Section, Down Syndrome, Female, Fetal Growth Retardation, Humans, Infant, Newborn, Placenta, Pregnancy, Pregnancy-Associated Plasma Protein-A, Retrospective Studies, Trisomy |
| الوصف: | OBJECTIVE: To examine the antenatal imaging features, intrapartum findings and early postpartum course of pregnancies with trisomy 21 (T21) at a tertiary hospital in the United Kingdom. METHODS: Women with pregnancies diagnosed with T21 on antenatal or post-mortem/postnatal karyotyping, from February 2010–2020. Outcome measures included antenatal imaging findings, fetal growth restriction (FGR), birthweight, mode of delivery and early neonatal outcomes. RESULTS: 76 women were included. There were six intrauterine deaths and 70 livebirths. Thirty-eight (50%) had an antenatal diagnosis and twenty-five (33%) had a suspected diagnosis but declined further testing. The diagnosis was unanticipated in 13 (17%). Cardiac anomalies (35.5%) were the most common antenatal anomaly. Doppler abnormalities were apparent in 48/73 (68%). Eighteen (25.7%) had antenatal FGR. The majority were delivered by Caesarean section, and 21.4% of babies weighed |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://discovery.ucl.ac.uk/id/eprint/10159966/1/T21_pre_typesetting.pdf; https://discovery.ucl.ac.uk/id/eprint/10159966/ |
| الاتاحة: | https://discovery.ucl.ac.uk/id/eprint/10159966/1/T21_pre_typesetting.pdf https://discovery.ucl.ac.uk/id/eprint/10159966/ |
| Rights: | open |
| رقم الانضمام: | edsbas.90819DC8 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |