Academic Journal
Relative survival and excess mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction
| العنوان: | Relative survival and excess mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction |
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| المؤلفون: | Brogan, R, Alabas, O, Almudarra, S, Hall, M, Dondo, TB, Mamas, M, Baxter, PD, Batin, PD, Curzen, N, De Belder, M, Ludman, P, Gale, C |
| بيانات النشر: | Sage |
| سنة النشر: | 2019 |
| المجموعة: | Keele University: Keele Research Repository |
| مصطلحات موضوعية: | RC666 Diseases of the circulatory (Cardiovascular) system |
| الوصف: | Background: High survival rates are commonly reported following primary percutaneous coronary intervention for ST-elevation myocardial infarction, with most contemporary studies reporting overall survival. Aims: The aim of this study was to describe survival following primary percutaneous coronary intervention for ST-elevation myocardial infarction corrected for non-cardiovascular deaths by reporting relative survival and investigate clinically significant factors associated with poor long-term outcomes. Methods and Results: Using the prospective UK Percutaneous Coronary Intervention registry, primary percutaneous coronary intervention cases (n=88,188; 2005-2013) were matched to mortality data for the UK populace. Crude five-year relative survival was 87.1% for the patients undergoing primary percutaneous coronary intervention and 94.7% for patients <55 years. Increasing age was associated with excess mortality up to four years following primary percutaneous coronary intervention (56-65 years: excess mortality rate ratio 1.61, 95% confidence interval 1.46-1.79; 66-75 years: 2.49, 2.26-2.75; >75 years: 4.69, 4.27-5.16). After four years, there was no excess mortality for ages 56-65 years (excess mortality rate ratio 1.27, 0.95-1.70), but persisting excess mortality for older groups (66-75 years: excess mortality rate ratio 1.72, 1.30-2.27; >75 years: 1.66, 1.15-2.41). Excess mortality was associated with cardiogenic shock (excess mortality rate ratio 6.10, 5.72-6.50), renal failure (2.52, 2.27-2.81), left main stem stenosis (1.67, 1.54-1.81), diabetes (1.58, 1.47-1.69), previous myocardial infarction (1.52, 1.40-1.65) and female sex (1.33, 1.26-1.41); whereas stent deployment (0.46, 0.42-0.50) especially drug eluting stents (0.27, 0.45-0.55), radial access (0.70, 0.63-0.71) and previous percutaneous coronary intervention (0.67, 0.60-0.75) were protective. Conclusions: Following primary percutaneous coronary intervention for ST-elevation myocardial infarction, long-term cardiovascular survival is ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://eprints.keele.ac.uk/id/eprint/3354/3/PPCI%20Relative%20Survival%20and%20Excess%20Mortality%20REVISED%20MM.pdf; Brogan, R, Alabas, O, Almudarra, S, Hall, M, Dondo, TB, Mamas, M orcid:0000-0001-9241-8890 , Baxter, PD, Batin, PD, Curzen, N, De Belder, M, Ludman, P and Gale, C (2019) Relative survival and excess mortality following primary percutaneous coronary intervention for ST-elevation myocardial infarction. European Heart Journal: Acute Cardiovascular Care, 8 (1). pp. 68-77. |
| DOI: | 10.1177/2048872617710790 |
| الاتاحة: | https://eprints.keele.ac.uk/id/eprint/3354/ https://eprints.keele.ac.uk/id/eprint/3354/3/PPCI%20Relative%20Survival%20and%20Excess%20Mortality%20REVISED%20MM.pdf https://doi.org/10.1177/2048872617710790 |
| Rights: | cc_by_nc_4 |
| رقم الانضمام: | edsbas.8F736741 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/2048872617710790 |
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