Academic Journal
Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model.
| العنوان: | Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. |
|---|---|
| المؤلفون: | Lozovaya, N., Gataullina, S., Tsintsadze, T., Tsintsadze, V., Pallesi-Pocachard, E., Minlebaev, M., Goriounova, N.A., Buhler, E., Watrin, F., Shityakov, S., Becker, A.J., Bordey, A., Milh, M., Scavarda, D., Bulteau, C., Dorfmuller, G., Delalande, O., Represa, A., Cardoso, C., Dulac, O., Ben-Ari, Y., Burnashev, N. |
| المصدر: | Lozovaya , N , Gataullina , S , Tsintsadze , T , Tsintsadze , V , Pallesi-Pocachard , E , Minlebaev , M , Goriounova , N A , Buhler , E , Watrin , F , Shityakov , S , Becker , A J , Bordey , A , Milh , M , Scavarda , D , Bulteau , C , Dorfmuller , G , Delalande , O , Represa , A , Cardoso , C , Dulac , O , Ben-Ari , Y & Burnashev , N 2014 , ' Selective suppression of excessive GluN2C expression rescues .... |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being |
| الوصف: | Tuberous sclerosis complex (TSC), caused by dominant mutations in either TSC1 or TSC2 tumour suppressor genes is characterized by the presence of brain malformations, the cortical tubers that are thought to contribute to the generation of pharmacoresistant epilepsy. Here we report that tuberless heterozygote Tsc1 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1038/ncomms5563 |
| الاتاحة: | https://research.vu.nl/en/publications/f546accd-3f98-40b2-9ff5-f06be793c1e1 https://doi.org/10.1038/ncomms5563 https://hdl.handle.net/1871.1/f546accd-3f98-40b2-9ff5-f06be793c1e1 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.8EE03058 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/ncomms5563 |
|---|