Academic Journal
Growth following solid organ transplantation in childhood
| العنوان: | Growth following solid organ transplantation in childhood |
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| المؤلفون: | Laster, M. L., Fine, R. N. |
| المصدر: | Pediatric Transplantation ; volume 18, issue 2, page 134-141 ; ISSN 1397-3142 1399-3046 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2014 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | One of the ultimate goals of successful transplantation in pediatric solid organ transplant recipients is the attainment of optimal final adult height. This manuscript will discuss the attainment of height following solid organ transplantation in pediatric recipients of kidney, liver, heart, lung, and small bowel transplantation. Age is a primary factor with younger recipients exhibiting the greatest immediate catch up growth. Graft function is a significant contributory factor with a reduction in glomerular filtration rate correlating with poor growth in kidney recipients and the need for re‐transplantation with impaired growth in liver recipients. The known adverse impact of steroids on growth has led to modification of steroid dosage and even to steroid withdrawal and steroid avoidance. In kidney and liver recipients, this has been associated with the development on occasion of acute rejection episodes. In infant heart transplantation, avoidance of maintenance corticosteroid immunosuppression is associated with normal growth velocity in the majority of patients. With marked improvement in patient and graft survival rates in pediatric organ graft recipients, it is timely that the quality of life issues, such as normal adult height, receive paramount attention. In general, normal growth post‐transplantation should be an achievable goal that results in normal adult height for many solid organ transplantation recipients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/petr.12219 |
| الاتاحة: | http://dx.doi.org/10.1111/petr.12219 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fpetr.12219 https://onlinelibrary.wiley.com/doi/pdf/10.1111/petr.12219 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.8E965189 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/petr.12219 |
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