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Expected values obtained from the decision model.
| العنوان: | Expected values obtained from the decision model. |
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| المؤلفون: | Dickens Odongo, Bernard Omech, Alfred Acanga |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Medicine, Biotechnology, Sociology, Cancer, Science Policy, Infectious Diseases, Computational Biology, united states dollar, household contact investigation, detect new cases, analytic modeling framework, 186 – 294, 52 %, household contacts presumed, economic evaluation using, existing data extracted, tb cases detected, standard passive case, strategies &# 8217, primary effectiveness measure, primary cost survey, patients either self, existing pcf programs, 193 , 17 , 14 – 22, tb screening yields, 8 %, tuberculosis control program, retrospective study approach |
| الوصف: | Introduction The standard passive case-finding strategy implemented by most developing countries is inadequate to detect new cases of Tuberculosis. A household contact investigation is an alternative approach. However, there is limited cost-effectiveness data to support planning and implementation in low and middle-income countries. The study aimed to evaluate the cost-effectiveness of adding household contact investigation (HCI) to the passive case-finding (PCF) strategy in the Tuberculosis control program in Southwestern Uganda. Methods We conducted an economic evaluation using a retrospective study approach and bottom-up costing (ingredients) techniques. It was a synthesis-based evaluation of existing data extracted from the District Health Information System (DHIS 2), TB registers, and a primary cost survey. The study compared two methods of Tuberculosis (TB) case finding (PCF and HCI) strategies. Regarding PCF, patients either self-reported their signs and symptoms or were prompted by healthcare workers. At the same time, HCI was done by home visiting and screening contacts of TB patients. Patients and household contacts presumed to have Tuberculosis were requested to produce samples for analysis. We applied a static decision-analytic modeling framework to examine both strategies’ costs and effectiveness. The study relied on cost and probability estimates from National Tuberculosis (TB) program data, activity costs, and published literature. It was performed from the societal and provider perspectives over 1.5 years across 12 facilities in Ntungamo, Sheema, and Rwampara Districts. The primary effectiveness measure was the number of TB cases detected (yield) and the number needed to screen (NNS). The TB yield was calculated from the number of patients screened during the period under study. The incremental cost-effectiveness ratio (ICER) was expressed as cost in 2021 US$ per additional TB case detected. We did not apply a discount rate because of the short analytic time horizon. Results The unit costs of ... |
| نوع الوثيقة: | still image |
| اللغة: | unknown |
| Relation: | https://figshare.com/articles/figure/Expected_values_obtained_from_the_decision_model_/24889183 |
| DOI: | 10.1371/journal.pone.0288761.s002 |
| الاتاحة: | https://doi.org/10.1371/journal.pone.0288761.s002 https://figshare.com/articles/figure/Expected_values_obtained_from_the_decision_model_/24889183 |
| Rights: | CC BY 4.0 |
| رقم الانضمام: | edsbas.8DB3B257 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1371/journal.pone.0288761.s002 |
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