Academic Journal
Exposure to mixed asymptomatic infections with Trypanosoma cruzi, Leishmania braziliensis and Leishmania chagasi in the human population of the greater Amazon
| العنوان: | Exposure to mixed asymptomatic infections with Trypanosoma cruzi, Leishmania braziliensis and Leishmania chagasi in the human population of the greater Amazon |
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| المؤلفون: | Mendes, Daniella G., Lauria‐Pires, Liana, Nitz, Nadjar, Lozzi, Silene P., Nascimento, Rubens J., Monteiro, Pedro S., Rebelo, Manuel M., Rosa, Ana de Cássia, Santana, Jaime M., Teixeira, Antonio R. L. |
| المصدر: | Tropical Medicine & International Health ; volume 12, issue 5, page 629-636 ; ISSN 1360-2276 1365-3156 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2007 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Summary Lack of conservation of the Amazon tropical rainforest has imposed severe threats to its human population living in newly settled villages, resulting in outbreaks of some infectious diseases. We conducted a seroepidemiological survey of 1100 inhabitants of 15 villages of Paço do Lumiar County, Brazil. Thirty‐five (3%) individuals had been exposed to Trypanosoma cruzi ( Tc ), 41 (4%) to Leishmania braziliensis ( Lb) and 50 (4.5%) to Leishmania chagasi ( Lc ) infections. Also, 35 cases had antibodies that were cross‐reactive against the heterologous kinetoplastid antigens. Amongst these, the Western blot assays revealed that 11 (1%) had Tc and Lb , that seven (0.6%) had Lc and Tc , and that 17 (1.6%) had Lb and Lc infections. All of these cases of exposures to mixed infections with Leishmania sp, and eight of 11 cases of Tc and Lb were confirmed by specific PCR assays and Southern hybridizations. Two cases had triple infections. We consider these asymptomatic cases showing phenotype and genotype markers consistent with mixed infections by two or more kinetoplastid flagellates a high risk factor for association with Psychodidae and Triatominae vectors blood feeding and transmitting these protozoa infections. This is the first publication showing human exposure to mixed asymptomatic kinetoplastid infections in the Amazon. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/j.1365-3156.2007.01831.x |
| الاتاحة: | http://dx.doi.org/10.1111/j.1365-3156.2007.01831.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-3156.2007.01831.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-3156.2007.01831.x |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.8D6BFCC9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/j.1365-3156.2007.01831.x |
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