Academic Journal
Sensing by wireless reading Ag/AgCl redox conversion on RFID tag : universal, battery-less biosensor design
| العنوان: | Sensing by wireless reading Ag/AgCl redox conversion on RFID tag : universal, battery-less biosensor design |
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| المؤلفون: | Larpant, Nutcha, Pham, Anh Duc, Shafaat, Atefeh, Gonzalez-Martinez, Juan F, Sotres, Javier, Sjöholm, Johan, Laiwattanapaisal, Wanida, Faridbod, Farnoush, Ganjali, Mohammad Reza, Arnebrant, Thomas, Ruzgas, Tautgirdas |
| بيانات النشر: | Malmö universitet, Institutionen för biomedicinsk vetenskap (BMV) Malmö universitet, Biofilms Research Center for Biointerfaces |
| سنة النشر: | 2019 |
| المجموعة: | Malmö University Electronic Publishing (MUEP) |
| مصطلحات موضوعية: | Multidisciplinary Sciences, Natural Sciences, Naturvetenskap |
| الوصف: | Massive integration of biosensors into design of Internet-of-Things (IoT) is vital for progress of healthcare. However, the integration of biosensors is challenging due to limited availability of battery-less biosensor designs. In this work, a combination of nanomaterials for wireless sensing of biological redox reactions is described. The design exploits silver nanoparticles (AgNPs) as part of the RFID tag antenna. We demonstrate that a redox enzyme, particularly, horseradish peroxidase (HRP), can convert AgNPs into AgCl in the presence of its substrate, hydrogen peroxide. This strongly changes the impedance of the tag. The presented example exploits gold nanoparticle (AuNP)-assisted electron transfer (ET) between AgNPs and HRP. We show that AuNP is a vital intermediate for establishing rapid ET between the enzyme and AgNPs. As an example, battery-less biosensor-RFID tag designs for H2O2 and glucose are demonstrated. Similar battery-less sensors can be constructed to sense redox reactions catalysed by other oxidoreductase enzymes, their combinations, bacteria or other biological and even non-biological catalysts. In this work, a fast and general route for converting a high number of redox reaction based sensors into battery-less sensor-RFID tags is described. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | Scientific Reports, 2019, 9; orcid:0000-0001-6937-3057; orcid:0000-0003-0304-7528; http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-3963; PMID 31506441; ISI:000484984700023; Scopus 2-s2.0-85072038367; Local 30524 |
| DOI: | 10.1038/s41598-019-49245-3 |
| الاتاحة: | http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-3963 https://doi.org/10.1038/s41598-019-49245-3 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.8D0DF98B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41598-019-49245-3 |
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