Academic Journal
P1271 The Astur-Frailty-IBD Study: Prevalence and factors associated with Frailty in elderly patients with Inflammatory Bowel Disease.
| العنوان: | P1271 The Astur-Frailty-IBD Study: Prevalence and factors associated with Frailty in elderly patients with Inflammatory Bowel Disease. |
|---|---|
| المؤلفون: | Carballo-Folgoso, L, Duque Alcorta, J M, Varela, P, De Francisco García, R, Armesto González, E, Mancebo Mata, A, Pérez-Martínez, I, Rodríguez López, P, De Jorge Turrión, M Á, Castaño-García, A, García-Pérez, C, Martínez Martín, G, Fernández-González, E, Chiminazzo, V, Díaz-Simal, A, Suarez, A, Riestra, S |
| المصدر: | Journal of Crohn's and Colitis ; volume 19, issue Supplement_1, page i2299-i2301 ; ISSN 1873-9946 1876-4479 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2025 |
| الوصف: | Background Frailty is a dynamic concept that provide a more comprehensive assessment of biological reserve and functional status rather than chronological age alone. The aim of this study is to evaluate the prevalence of frailty and to analyse the factors associated with this condition in elderly inflammatory bowel disease (IBD) patients. Methods As part of the Astur-Frailty-IBD study (a multicentre prospective study of elderly IBD patients attended at three hospitals in Asturias, Spain), we present the baseline data of the cohort. We recruited all consecutive IBD patients ≥ 60 years during outpatient visits between March 1 and June 30, 2024. Demographic data and clinical characteristics of IBD were collected from the medical records and disease activity was assessed using clinical scores and biomarkers. All the patients were surveyed by face-to-face questionaries. Frailty was assessed using the Fried Frailty Phenotype which defines non-frail (0 criteria), prefrail (1-2), and frail phenotype (≥ 3 criteria). Comorbidity was assessed using Charlson Comorbidity Index (CCI) and Cumulative Illness Rating Scale-Geriatric (CIRS-G). Univariable and multivariable ordinal logistic regression model was performed. Results A total of 612 IBD patients (median age 68.8 years, 50.2% females, 56.4% Crohn’s disease, median duration of the disease 15 years) were included in our study. One hundred and three (16.8%) patients were considered frail, 302 (49.3%) prefrail and 207 (33.8%) non-frail. Association of demographic, social and clinical factors according to different frailty levels are shown in Table 1. Univariate analysis showed the factors that are independently associated with increased risk of frailty were higher age, female gender, higher BMI, osteoarticular disease, polypharmacy, clinical activity, faecal calprotectin ≥ 250 μg/g, currently use of steroids, immunomodulator, or biologics, CCI ≥4, and CIRS-G ≥ 3. In contrast, ulcerative colitis, IBD-Unclassified and having good family support were associated with a ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/ecco-jcc/jjae190.1445 |
| الاتاحة: | https://doi.org/10.1093/ecco-jcc/jjae190.1445 https://academic.oup.com/ecco-jcc/article-pdf/19/Supplement_1/i2299/61549003/jjae190.1445.pdf |
| Rights: | https://academic.oup.com/pages/standard-publication-reuse-rights |
| رقم الانضمام: | edsbas.8C524E5C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ecco-jcc/jjae190.1445 |
|---|