Academic Journal
The impact of geometry, intramural friction, and pressure on the antegrade longitudinal motion of the arterial wall : a phantom and finite element study
| العنوان: | The impact of geometry, intramural friction, and pressure on the antegrade longitudinal motion of the arterial wall : a phantom and finite element study |
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| المؤلفون: | Sjöstrand, Sandra, Widerström, Alice, Svensson, Ingrid, Segers, Patrick, Erlöv, Tobias, Ahlgren, Åsa Rydén, Cinthio, Magnus |
| المصدر: | PHYSIOLOGICAL REPORTS ; ISSN: 2051-817X |
| سنة النشر: | 2023 |
| المجموعة: | Ghent University Academic Bibliography |
| مصطلحات موضوعية: | Technology and Engineering, Medicine and Health Sciences, Physiology (medical), Physiology |
| الوصف: | Longitudinal motion of the carotid arterial wall, as measured with ultrasound, has shown promise as an indicator of vascular health. The underlying mechanisms are however not fully understood. We have found, in in vivo studies, that blood pressure has a strong relation to the antegrade longitudinal displacement in early systole. Further, we have identified that a tapered geometry and the intramural friction in-between two parts of a vessel wall influence the longitudinal displacement. We therefore studied the interaction between pressure, vessel geometry and intramural friction, tapered and straight ultrasound phantoms in a paralleled hydraulic bench study and corresponding numerical models. Profound antegrade longitudinal motion was induced in the innermost part of both tapered phantoms and the numerical models, but to a lesser extent when intramural friction was increased in the simulations. Strong correlations (R = 0.82-0.96; p < 1e-3; k = 9.3-14 mu m/mmHg) between longitudinal displacement and pulse pressure were found in six of seven regions of interest in tapered phantoms. The motion of the straight phantom and the corresponding numerical model was smaller, on average zero or close to zero. This study demonstrates that tapering of the lumen, low intramural friction, and pressure might be important conducive features to the antegrade longitudinal motion of the arterial wall in vivo. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://biblio.ugent.be/publication/01H396F58B2PYNDWWW5ZS46WDV; http://hdl.handle.net/1854/LU-01H396F58B2PYNDWWW5ZS46WDV; http://doi.org/10.14814/phy2.15746; https://biblio.ugent.be/publication/01H396F58B2PYNDWWW5ZS46WDV/file/01H396H69RSGGMPY1NWRYXMGY3 |
| DOI: | 10.14814/phy2.15746 |
| الاتاحة: | https://biblio.ugent.be/publication/01H396F58B2PYNDWWW5ZS46WDV http://hdl.handle.net/1854/LU-01H396F58B2PYNDWWW5ZS46WDV https://doi.org/10.14814/phy2.15746 https://biblio.ugent.be/publication/01H396F58B2PYNDWWW5ZS46WDV/file/01H396H69RSGGMPY1NWRYXMGY3 |
| Rights: | Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.8C1DE3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.14814/phy2.15746 |
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