Academic Journal
92 Presence and Etiology of Erectile Dysfunction in Peyronie's Disease as Demonstrated by Color Doppler Duplex Ultrasound
| العنوان: | 92 Presence and Etiology of Erectile Dysfunction in Peyronie's Disease as Demonstrated by Color Doppler Duplex Ultrasound |
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| المؤلفون: | Haehn, D, Pathak, R, Parikh, K, Ball, C, Broderick, G |
| المصدر: | The Journal of Sexual Medicine ; volume 19, issue Supplement_1, page S47-S48 ; ISSN 1743-6109 1743-6095 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2022 |
| الوصف: | Introduction Peyronie's Disease (PD) can coexist with erectile dysfunction (ED). International guidelines recommend that management of PD include an assessment of each patient's ability to initiate and sustain erection. PD causes significant stress to the patient and his partner; that distress may limit their ability to assess adequacy of penile rigidity. Further complicating evaluations based on history is the fact that PDE5-Inhibitor use is common. Objective The primary aim of this study is to non-invasively assess vascular erectile integrity in the setting of PD. Methods 1490 patients who underwent intracavernous injection (ICI) followed by Color Doppler Duplex Ultrasound (CDDU) at our institution were retrospectively analyzed. CDDU findings were recorded following injection of low dose alprostadil (10-20 mcg) and again after a period of privacy and visual sexual stimulation. CCDU findings including peak systolic velocities (PSV), and resistive indices (RIs) were recorded. Arterial insufficiency (AI) was defined as either a post-stimulation PSV < 25 cm/sec (severe AI) or a PSV 25-34.9, RI ≥ 0.9(mild AI). Cavernous Venous Occlusion Disease (CVOD) was defined as post-stimulation PSV ≥ 35 cm/sec with RI < 0.9. Mixed was defined as post-stimulation PSV 25-34.9 with RI < 0.9. Vascular normal was defined as post-stim PSV ≥ 35 with RI ≥ 0.9. Results Our cohort of 1490 patients included 900 (60.4%) with a complaint of both PD + ED; 461 (30.9%) with complaint of ED only and 129 (8.7%) with complaint of PD only. Following ICI with PGE1, 310 men were found to have PD and 767 were found to have PD + ED. Patients with a CDDU confirmed diagnosis of PD alone were younger (median: 56.9 vs. 60.8 y, p < 0.001), less likely to have hypertension [103/310 (33.2%) vs. 365/767 (47.6%), p < 0.001], less likely to have used PDE-5 inhibitor [219/310 (70.6%) vs. 616/767 (80.3%), p < 0.001], and less likely to have failed to a PDE-5 inhibitor [142/219 (64.8%) vs. 484/616 (78.6%, p ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1016/j.jsxm.2022.01.104 |
| الاتاحة: | https://doi.org/10.1016/j.jsxm.2022.01.104 https://api.elsevier.com/content/article/PII:S1743609522001370?httpAccept=text/xml https://api.elsevier.com/content/article/PII:S1743609522001370?httpAccept=text/plain https://academic.oup.com/jsm/article-pdf/19/Supplement_1/S47/48969502/jsm_19_4_supplement_1_s47a.pdf |
| Rights: | https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model |
| رقم الانضمام: | edsbas.8BF4DD39 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jsxm.2022.01.104 |
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