التفاصيل البيبلوغرافية
| العنوان: |
Sleep and gastrointestinal problems in hospitalized children with Autism Spectrum Disorder (ASD) |
| المؤلفون: |
Taylor, Briana J, Pedersen, Kahsi, Siegel, Matthew, Autism, Developmental Disorders Inpatient Research Collaborative |
| المصدر: |
Costas T. Lambrew Research Retreat 2020 |
| بيانات النشر: |
MaineHealth Knowledge Connection |
| سنة النشر: |
2020 |
| مصطلحات موضوعية: |
Child, Humans, Autism Spectrum Disorder, Hospitalized, Sleep, Gastrointestinal Diseases, Behavior and Behavior Mechanisms, Gastroenterology, Pediatrics, psy, edu |
| الوصف: |
Background: Sleep and gastrointestinal (GI) problems are prevalent medical comorbidities in children with autism spectrum disorder (ASD). Sleep and GI problems are correlated with one another in both ASD and non-ASD children; however, mechanisms underlying this association are unclear. Anxiety is also highly prevalent in ASD and has been identified as a potential mediator of the sleep-GI association in non-ASD individuals. The role of anxiety in the sleep-GI association in ASD is unclear. Objectives: To determine if anxiety symptoms statistically mediate associations between sleep problems and GI problems in a sample of psychiatrically hospitalized children with ASD. Methods: Data from the Autism Inpatient Collection (AIC) were used for this analysis. The AIC is a multi-site study of children with ASD admitted to one of six inpatient units specialized for the psychiatric treatment of children with ASD. Caregivers provided information regarding medical comorbidities and completed the Child Behavior Checklist (CBCL). Autism diagnosis, autism severity, verbal ability, and intellectual functioning were assessed by research-reliable Autism Diagnostic Observation Schedule-2 and the Leiter International Performance Scale-3. Complete data were available in 276 patients. Logistic regressions were used to determine if caregiver-reported sleep problems predicted GI problems independent of age, sex, autism severity, verbal ability, intellectual functioning, and anxiety symptoms. Sobel tests were used to determine if anxiety symptoms statistically mediated associations between sleep and GI problems. A sensitivity analysis was used to examine if results held when the CBCL Anxiety Problem question about nightmares was removed from the total score. Exploratory logistic regressions examined items within the CBCL Anxiety Problem subscale to determine if specific indicators of anxiety were driving analyses. Results: Prior to adjusting for anxiety symptoms, Logistic regression analyses revealed that children with ASD and a sleep ... |
| نوع الوثيقة: |
text |
| اللغة: |
unknown |
| Relation: |
https://knowledgeconnection.mainehealth.org/lambrew-retreat-2020/67 |
| الاتاحة: |
https://knowledgeconnection.mainehealth.org/lambrew-retreat-2020/67 |
| Rights: |
undefined |
| رقم الانضمام: |
edsbas.897A29AF |
| قاعدة البيانات: |
BASE |