التفاصيل البيبلوغرافية
| العنوان: |
Histopathology of lung, liver and splenic lesions. |
| المؤلفون: |
Derek R. Stein (10953929), Bryce M. Warner (11547649), Jonathan Audet (328818), Geoff Soule (4495729), Vinayakumar Siragam (455948), Patrycja Sroga (11547652), Bryan D. Griffin (8677521), Anders Leung (375755), Allen Grolla (59441), Kevin Tierney (6410933), Alix Albietz (11547655), Darwyn Kobasa (18296), Abdulmajid S. Musa (11547658), Adama Ahmad (11547661), Afolabi M. Akinpelu (11547664), Nwando Mba (7907681), Rebecca Rosenke (191750), Dana P. Scott (9461153), Greg Saturday (712945), Chikwe Ihekweazu (812587), David Safronetz (119343) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Medicine, Microbiology, Biotechnology, Ecology, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, world health organization, renewed international effort, notably respiratory failure, considerable phenotypic heterogeneity, accelerated research leading, evaluating medical countermeasures, reduce lf morbidity, div >< p, lethal lf infections, effective countermeasures, lf ), west africa, vivo <, three isolates, results suggest, priority pathogen, potential vaccines, pathogenesis characteristics, nhp model, nhp ), limiting factor |
| الوصف: |
Thin sections of formalin fixed tissue specimens collected at the time of severe disease from NHPs infected with Lassa virus Josiah, NML-33 and NML-57 isolates were prepared and stained using standard histopathological methods (Hematoxylin & Eosin, 200X bar = 20μm). Specimens from representative animals demonstrated a. Lung—Josiah—normal b. Lung—NML-33—intestinal pneumonia: alveolar septa expanded by edema, fibrin and inflammatory cells (yellow arrow) (fibrin = black arrow) (asterisk = edema) c. Lung—NML-57 — normal d. Liver—Josiah—focal minimal fibrin deposits and neutrophilic infiltrates (yellow arrow) e. Liver—NML-33—multifocal fibrin deposits with neutrophilic histiocytic infiltrates (yellow arrows) f. Liver -NML-57—normal g. Spleen—Josiah—normal h. Spleen NML-33—multifocal red pulp necrosis (black arrows) i. Spleen—NML-57—normal. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Histopathology_of_lung_liver_and_splenic_lesions_/16785535 |
| DOI: |
10.1371/journal.ppat.1009966.g006 |
| الاتاحة: |
https://doi.org/10.1371/journal.ppat.1009966.g006 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.88E75990 |
| قاعدة البيانات: |
BASE |