Academic Journal
The influence of intraoperative hemodynamic parameters on the results of combined kidney and pancreas transplantation ; Влияние интраоперационных показателей гемодинамики на результаты сочетанной трансплантации почки и поджелудочной железы
| العنوان: | The influence of intraoperative hemodynamic parameters on the results of combined kidney and pancreas transplantation ; Влияние интраоперационных показателей гемодинамики на результаты сочетанной трансплантации почки и поджелудочной железы |
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| المؤلفون: | M. Sh. Khubutiya, M. V. Lebedev, N. K. Kuznetsova, A. M. Talyzin, A. G. Balkarov, S. V. Zhuravel, М. Ш. Хубутия, М. В. Лебедев, Н. К. Кузнецова, А. М. Талызин, А. Г. Балкаров, С. В. Журавель |
| المساهمون: | Исследование проводилось без спонсорской поддержки |
| المصدر: | Transplantologiya. The Russian Journal of Transplantation; Том 16, № 4 (2024); 422-437 ; Трансплантология; Том 16, № 4 (2024); 422-437 ; 2542-0909 ; 2074-0506 |
| بيانات النشر: | IPO Association of Transplantologists |
| سنة النشر: | 2024 |
| المجموعة: | Transplantology (E-Journal) / Трансплантология |
| مصطلحات موضوعية: | госпитальная выживаемость реципиентов, intraoperative hemodynamic parameters, mean arterial pressure, graft hospital survival, recipient hospital survival, интраоперационные показатели гемодинамики, среднее артериальное давление, госпитальная выживаемость трансплантатов |
| الوصف: | Introduction. Reperfusion syndrome has been proven to impact the early results of simultaneous pancreas and kidney transplantation. The optimal values of hemodynamic parameters at the moment of reperfusion of the kidney graft and the pancreas graft have been the subject of discussion in relation to possible early complications and outcomes of simultaneous pancreas and kidney transplantation. This issue needs additional research.The objective was to evaluate how the intraoperative hemodynamic parameters may influence early results of simultaneous pancreas and kidney transplantation.Material and methods. The retrospective study was conducted to analyze the impact of intraoperative hemodynamic parameters on the early results of treatment in 83 patients who underwent simultaneous pancreas and kidney transplantation in the N.V. Sklifosovsky Research Institute for Emergency Medicine in the period from 2008 to 2023.Given the primary ROC analysis results, we allocated the patients into 2 groups, according to their mean arterial pressure (MAP) values at reperfusion. Group I consisted of patients with MAP<90 mmHg (n=21), group II included patients with MAP>90 mmHg (n=62). The characteristics of donors and recipients were comparable between the groups (p>0.05). The intraoperative hemodynamic parameters of the recipients (MAP, central venosus pressure, heart rate) were analyzed at the beginning of surgery, at reperfusion stages, at the time of making the interintestinal anastomosis, and on surgery completion; the incidence of postoperative complications was studied; the primary functions of the kidney and pancreas grafts were evaluated; the in-hospital graft and recipient survival rates were calculated.Results. The median values of MAP (mm Hg) were significantly lower in group I compared to those in group II at all stages of surgery, except for the surgery beginning: 87 (86;87) mmHg versus 101 (97;104) mmHg at the time of the kidney graft reperfusion; 89 (83;95) mmHg versus 97 (93;102) mmHg at the time of the ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
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| DOI: | 10.23873/2074-0506-2024-16-4-422-437 |
| الاتاحة: | https://www.jtransplantologiya.ru/jour/article/view/936 https://doi.org/10.23873/2074-0506-2024-16-4-422-437 |
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| رقم الانضمام: | edsbas.88987177 |
| قاعدة البيانات: | BASE |
| DOI: | 10.23873/2074-0506-2024-16-4-422-437 |
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