Academic Journal
Validation of Echocardiographic Measurements in Patients with Pulmonary Embolism in the RIETE Registry
| العنوان: | Validation of Echocardiographic Measurements in Patients with Pulmonary Embolism in the RIETE Registry |
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| المؤلفون: | Lyhne, Mads Dam, Bikdeli, Behnood, Dudzinski, David M., Muriel-García, Alfonso, Kabrhel, Christopher, Sancho-Bueso, Teresa, Pérez-David, Esther, Lobo, José Luis, Alonso-Gómez, Ángel, Jiménez, David, Monreal, Manuel |
| المصدر: | TH Open ; volume 08, issue 01, page e1-e8 ; ISSN 2512-9465 |
| بيانات النشر: | Georg Thieme Verlag KG |
| سنة النشر: | 2024 |
| الوصف: | Background In acute pulmonary embolism (PE), echocardiographic identification of right ventricular (RV) dysfunction will inform prognostication and clinical decision-making. Registro Informatizado Enfermedad TromboEmbolica (RIETE) is the world's largest registry of patients with objectively confirmed PE. The reliability of site-reported RV echocardiographic measurements is unknown. We aimed to validate site-reported key RV echocardiographic measurements in the RIETE registry. Methods Fifty-one randomly chosen patients in RIETE who had transthoracic echocardiogram (TTE) performed for acute PE were included. TTEs were de-identified and analyzed by a core laboratory of two independent observers blinded to site-reported data. To investigate reliability, intraclass correlation coefficients (ICCs) and Bland–Altman plots between the two observers, and between an average of the two observers and the RIETE site-reported data were obtained. Results Core laboratory interobserver variations were very limited with correlation coefficients >0.8 for all TTE parameters. Agreement was substantial between core laboratory observers and site-reported data for key parameters including tricuspid annular plane systolic excursion (ICC 0.728; 95% confidence interval [CI], 0.594–0.862) and pulmonary arterial systolic pressure (ICC 0.726; 95% CI, 0.601–0.852). Agreement on right-to-left ventricular diameter ratio (ICC 0.739; 95% CI, 0.443–1.000) was validated, although missing data limited the precision of the estimates. Bland–Altman plots showed differences close to zero. Conclusion We showed substantial reliability of key RV site-reported measurements in the RIETE registry. Ascertaining the validity of such data adds confidence and reliability for subsequent investigations. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1055/s-0043-1777765 |
| DOI: | 10.1055/s-0043-1777765.pdf |
| الاتاحة: | http://dx.doi.org/10.1055/s-0043-1777765 http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0043-1777765.pdf |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.858C373 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1055/s-0043-1777765 |
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