Academic Journal
Diagnostic accuracy of intraoperative frozen section for margin evaluation of oral cavity squamous cell carcinoma
| العنوان: | Diagnostic accuracy of intraoperative frozen section for margin evaluation of oral cavity squamous cell carcinoma |
|---|---|
| المؤلفون: | Ali, Javaria P, Mallick, Bakhtawar Allauddin, Rashid, Khushbakht, Malik, Umair Arshad, Hashmi, Atif Ali, Zia, Shamail, Irfan, Muhammad, Khan, Amir, Faridi, Naveen |
| المصدر: | Section of Internal Medicine |
| بيانات النشر: | eCommons@AKU |
| سنة النشر: | 2024 |
| المجموعة: | The Aga Khan University: eCommons@AKU |
| مصطلحات موضوعية: | Diagnostic accuracy, Frozen section, Intraoperative frozen section, Oral cavity squamous cell carcinoma, Oral tumors, Sensitivity, Specificity, Cells, Emergency Medicine, Infectious Disease, Oncology, Tissues |
| الوصف: | Objectives: Intraoperative frozen-section evaluation is a valuable technique for detecting positive margins intraoperatively for oral squamous cell carcinoma. We conducted this study to determine the diagnostic accuracy of frozen section in detecting margin status and the effect of tumor grade and stage on diagnostic accuracy.Results: A total of 251 biopsy-proven cases of oral squamous cell carcinoma were included in this study. The tissue specimen resected during surgery was sent to the laboratory for frozen section evaluation. The frozen section results were then compared with the permanent section results to determine the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy. The mean age of the patients included in the study was 51.65 ± 10.03 years, with male predominance (55.4%). The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of frozen section were 88.81%, 94.84%, 95.20%, 88.10%, and 91.63%, respectively. We conclude that frozen section is a useful technique in determining the margin status intraoperatively in oral cancers, with high diagnostic accuracy. Moreover, certain clinical parameters such as age, gender, disease duration, and tumor stage and grade appear to affect the diagnostic accuracy of frozen section. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| Relation: | https://ecommons.aku.edu/pakistan_fhs_mc_med_intern_med/251; https://ecommons.aku.edu/context/pakistan_fhs_mc_med_intern_med/article/1252/viewcontent/Diagnostic_accuracy_of_intraoperative.pdf |
| الاتاحة: | https://ecommons.aku.edu/pakistan_fhs_mc_med_intern_med/251 https://ecommons.aku.edu/context/pakistan_fhs_mc_med_intern_med/article/1252/viewcontent/Diagnostic_accuracy_of_intraoperative.pdf |
| رقم الانضمام: | edsbas.844940D2 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |