Academic Journal
The Role of Cognitive Deficits in Borderline Personality Disorder with Early Traumas: A Mediation Analysis
| العنوان: | The Role of Cognitive Deficits in Borderline Personality Disorder with Early Traumas: A Mediation Analysis |
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| المؤلفون: | Paola Bozzatello, Cecilia Blua, Claudio Brasso, Paola Rocca, Silvio Bellino |
| المساهمون: | Paola Bozzatello, Cecilia Blua, Claudio Brasso, Paola Rocca, Silvio Bellino |
| سنة النشر: | 2023 |
| المجموعة: | Università degli studi di Torino: AperTo (Archivio Istituzionale ad Accesso Aperto) |
| مصطلحات موضوعية: | Executive functions, personality disorders, social cognition, BPD psychopathology |
| الوصف: | (1) Background: although studies of cognitive functions are still limited in borderline per sonality disorder (BPD), the initial evidence suggested that BPD patients have deficits of executive functions and social cognition. In addition, patients who report physical and psychic traumatic ex periences in childhood and adolescence show considerable neurocognitive impairment and severe BPD symptoms. The present study has a twofold aim: (1) to evaluate the differences in neurocogni tive performances between BPD patients and healthy controls and (2) to verify in the BPD patients group whether neurocognitive deficits have the role of mediating the effect of early traumas on BPD psychopathology. (2) Methods: 69 subjects were enrolled: 38 outpatients with a diagnosis of BPD (DSM-5) and 31 healthy controls. BPD patients were tested with the Borderline Personality Disorder Severity Index (BPDSI), and the Childhood Trauma Questionnaire–Short Form (CTQ-SF). All sub jects were evaluated with the Iowa Gambling task (IGT), the Berg card sorting test (BCST), the Tower of London task (ToL), and the Reading-the-mind-in-the-eyes-test (RMET). Statistical analysis was performed with the analysis of variance to compare the cognitive performances between BPD pa tients and controls. A mediation analysis was conducted with the Sobel Test in the BPD patients group. The significance level was p ≤ 0.05. (3) Results: significant differences between the two groups were found for several parameters of all the cognitive tests examined: BCST, IGT, ToL, and RMET. Mediation analysis with the Sobel test demonstrated that the percentage of correct answers in the BCST (BCSTc) and the RMET score significantly mediated the relation between the CTQ total score and BPDSI total score. (4) Conclusions: BPD patients showed an impairment of the following exec utive functions: set shifting, decision making, planning and problem solving, and social cognition abilities, in comparison with controls. Our results suggested that the effect of early trauma on BPD ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | volume:12; issue:3; firstpage:787; lastpage:798; numberofpages:12; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/2318/1887774; https://www.mdpi.com/2077-0383/12/3/787 |
| DOI: | 10.3390/jcm12030787 |
| الاتاحة: | https://hdl.handle.net/2318/1887774 https://doi.org/10.3390/jcm12030787 https://www.mdpi.com/2077-0383/12/3/787 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.8431C9DC |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/jcm12030787 |
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