التفاصيل البيبلوغرافية
| العنوان: |
Cognitive Profile and Cardiovascular Risk Factors in Older Adults with Mild Cognitive Impairment |
| المؤلفون: |
Vázquez-de Sebastián, Julia, Ortiz Zúñiga, Ãngel Michael, Ciudin, Andreea, Ars, Joan, Inzitari, Marco, Simó Canonge, Rafael, Hernández, Cristina, Ariño-Blasco, Sergio, Barahona, MarÃa-José, Franco, Maite, Gironès, Xavier, Crespo Maraver, MarÃa Cruz, Rovira, Joan Carles, Castellano-Tejedor, Carmina |
| سنة النشر: |
2024 |
| المجموعة: |
Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB |
| مصطلحات موضوعية: |
Cardiovascular risk factors, Type 2 diabetes, Cognitive impairment, Neuropsychological profile, Mild cognitive impairment, Older adults |
| الوصف: |
The prevalence of cardiovascular risk factors (CVRFs) in the older adults population and their specific impact on their cognitive profiles still requires further research. For this purpose, a cross-sectional study was carried out to describe the presence of CVRFs and their association with cognitive performance in a sample of older adults (65-85 years old) with Mild Cognitive Impairment (MCI). Participants (n = 185) were divided into three groups concerning their cardiovascular risk level determined by the presence of different CVRFs, including Type 2 Diabetes (T2D), dyslipidemia, hypertension, and obesity. The primary outcome measures were the participant's scores in the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Sociodemographic, clinical, and psychosocial data were collected. Non-parametrical statistical analyses and effect sizes were calculated. Findings revealed that a greater presence of CVRFs was not associated with a worse overall cognitive performance. High-risk patients were more likely to have significantly worse performance in the attentional domain compared to medium-risk (p = 0.029, r = 0.42) and compared to low-risk (p = 0.041, r = 0.35), specifically in the digits repetition subtest (p = 0.042). T2D alone was the CVRF associated with cognitive differences (p = 0.037, r = 0.32), possibly mediated by the duration of the condition. Consequently, a higher presence of CVRFs did not lead to a worse overall cognitive performance. However, high-risk individuals were more likely to experience cognitive impairment, particularly in the attentional domain. T2D played a significant role in these cognitive profile differences, possibly influenced by its duration. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
International journal of environmental research and public health; Vol. 21 (april 2024); https://ddd.uab.cat/record/292053; urn:10.3390/ijerph21040500; urn:oai:ddd.uab.cat:292053; urn:pmcid:PMC11050679; urn:pmid:38673411; urn:oai:pubmedcentral.nih.gov:11050679 |
| الاتاحة: |
https://ddd.uab.cat/record/292053 |
| Rights: |
open access ; Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. ; https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.83D3D6FC |
| قاعدة البيانات: |
BASE |