Academic Journal

Systemic effects after colorectal insufflation of oxygen/ozone in rabbit

التفاصيل البيبلوغرافية
العنوان: Systemic effects after colorectal insufflation of oxygen/ozone in rabbit
المؤلفون: V. Bocci, E. Borrelli, F. Corradeschi, VALACCHI, Giuseppe
المساهمون: V., Bocci, E., Borrelli, F., Corradeschi, Valacchi, Giuseppe
سنة النشر: 2000
المجموعة: Università degli Studi di Ferrara: CINECA IRIS
الوصف: urrently, with reappraisal of ozone therapy, it has been utilized worldwide in research and clinical field. Most of the studies investigating effects of ozone on blood parameters are conducted by directly ozonating the blood. Rectal insufflation is a simple, easy and inexpensive method of delivering ozone. Little is known how these gases affect some fundamental hemorheologic parameters when given by insufflation. We aimed to investigate the effects of colorectally insufflated oxygen-ozone on red blood cell rheology in rabbits. Rabbits were divided into Group 1 (control); Groups 2, 3 and 4 (oxygen rectally insufflated respectively for 15, 21 and 36 days); Groups 5, 6 and 7 (ozone rectally insufflated respectively for 15, 21 and 36 days). Erythrocyte deformability, aggregation and osmotic fragility were determined from blood samples at the end of each treatment period. Our study showed an improvement in deformability, a decrease in aggregation and an increase in fragility following a 15 day ozone treatment. With longer ozone application the changes in aggregation and fragility returned back to control levels, however its effect on deformability sustained. Therefore, more than two weeks ozone insufflation may induce adaptation to changes induced by ozone suggesting its systemic effects.
نوع الوثيقة: article in journal/newspaper
وصف الملف: ELETTRONICO
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/wos/not available; volume:28; firstpage:109; lastpage:113; journal:INTERNATIONAL JOURNAL OF MEDICINE, BIOLOGY AND THE ENVIRONMENT; http://hdl.handle.net/11392/1672488; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0034435172
الاتاحة: http://hdl.handle.net/11392/1672488
رقم الانضمام: edsbas.839E52D2
قاعدة البيانات: BASE