Academic Journal
Pulmonary arteriovenous malformations associated with migraine with aura
العنوان: | Pulmonary arteriovenous malformations associated with migraine with aura |
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المؤلفون: | Post, M C, van Gent, M W F, Plokker, H W M, Westermann, C J J, Kelder, J C, Mager, J J, Overtoom, T T, Schonewille, W J, Thijs, Vincent, Snijder, R J |
سنة النشر: | 2009 |
المجموعة: | KU Leuven: Lirias |
الوصف: | Migraine with aura (MA) is associated with cardiac right-to-left shunt. We prospectively studied the association between pulmonary arteriovenous malformations (PAVMs) and MA in hereditary hemorrhagic teleangiectasia (HHT).All 220 consecutive HHT patients who underwent a high-resolution chest computed tomography for PAVM screening, were included prospectively. Prior to screening a structured validated headache questionnaire was completed by 196 patients (57% female, mean age 45+/-15 years). Two neurologists diagnosed migraine according to the International Headache Society Criteria.A PAVM was present in 70 (36%) patients. The prevalence of MA was 24% in the presence of a PAVM compared to 6% in the absence of a PAVM (OR 4.6: 95% CI 1.84-11.2; p=0.001), and MA was an independent predictor for the presence of PAVM using multivariate analysis (OR 3.6: 95% CI 1.21-10.5; p=0.02). A PAVM was present in 68% of the patients with MA compared to 32% in the non-migraine controls (OR 4.6: 95% CI 1.84-11.2; p=0.001), and a PAVM was an independent predictor for MA using multivariate analysis (OR 3.0: 95% CI 1.00-9.20; p=0.05).PAVMs are associated with MA in HHT patients. ; status: published |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 0903-1936 |
Relation: | European Respiratory Journal vol:34 issue:4 pages:882-887; https://lirias.kuleuven.be/handle/123456789/237626; http://erj.ersjournals.com/cgi/pmidlookup?view=long&pmid=19324948 |
الاتاحة: | https://lirias.kuleuven.be/handle/123456789/237626 http://erj.ersjournals.com/cgi/pmidlookup?view=long&pmid=19324948 |
رقم الانضمام: | edsbas.83089D71 |
قاعدة البيانات: | BASE |
تدمد: | 09031936 |
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